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Comparison of analgesic effects between programmed intermittent epidural boluses and continuous epidural infusion after cesarean section: a randomized controlled study
Yu Jeong Bang, Heejoon Jeong, RyungA Kang, Ji-Hee Sung, Suk-Joo Choi, et al.
Korean J Anesthesiol. 2024;77(3):374-383.

Review Article

January 17, 2024


Intraoperative pediatric electroencephalography monitoring: an updated review
Ian Yuan, Choon L. Bong, Jerry Y. Chao
Korean J Anesthesiol. 2024;77(3):289-305.

Intraoperative electroencephalography (EEG) monitoring under pediatric anesthesia has begun to attract increasing interest, driven by the availability of pediatric-specific EEG monitors and the realization that traditional dosing methods based on patient movement or changes in hemodynamic response often lead to imprecise dosing, especially in younger infants who may experience adverse events (e.g., hypotension) due to excess anesthesia. EEG directly measures the effects of anesthetics on the brain, which is the target end-organ responsible for inducing loss of consciousness. Over the past ten years, research on anesthesia and computational neuroscience has improved our understanding of intraoperative pediatric EEG monitoring and expanded the utility of EEG in clinical practice. ...

Review Article

January 29, 2024


Perioperative management of patients with cardiac implantable electronic devices
Minsu Kim, Chang Hee Kwon
Korean J Anesthesiol. 2024;77(3):306-315.

The use of cardiac implantable electronic devices (CIEDs) has increased significantly in recent years. Consequently, more patients with CIEDs will undergo surgery during their lifetime, and thus the involvement of anesthesiologists in the perioperative management of CIEDs is increasing. With ongoing advancements in technology, many types of CIEDs have been developed, including permanent pacemakers, leadless pacemakers, implantable cardioverter defibrillators, cardiac resynchronization therapy-pacemakers/defibrillators, and implantable loop recorders. The functioning of CIEDs exposed to an electromagnetic field can be affected by electromagnetic interference, potential sources of which can be found in the operating room. Thus, to prevent potential adverse events caused by electromagnetic interference in the operating room, anesthesiologists must have knowledge...

Statistical Round

April 29, 2024


Alternatives to the P value: connotations of significance
Junyong In, Dong Kyu Lee
Korean J Anesthesiol. 2024;77(3):316-325.

The statistical significance of a clinical trial analysis result is determined by a mathematical calculation and probability based on null hypothesis significance testing. However, statistical significance does not always align with meaningful clinical effects; thus, assigning clinical relevance to statistical significance is unreasonable. A statistical result incorporating a clinically meaningful difference is a better approach to present statistical significance. Thus, the minimal clinically important difference (MCID), which requires integrating minimum clinically relevant changes from the early stages of research design, has been introduced. As a follow-up to the previous statistical round article on P values, confidence intervals, and effect sizes, in this article, we present hands-on examples of MCID and...

Clinical Research Article

February 20, 2024


Comparison of preemptive and preventive intravenous acetaminophen on opioid consumption in pediatrics undergoing posterior spinal fusion surgery: a randomized controlled trial
Yeon Ju Kim, Ha-Jung Kim, Sehee Kim, Hyungtae Kim, Choon Sung Lee, et al.
Korean J Anesthesiol. 2024;77(3):326-334.

Background: Posterior spinal fusion (PSF), commonly used for adolescent idiopathic scoliosis (AIS), causes severe postoperative pain. Intravenous (IV) administration of acetaminophen has shown promise for opioid-sparing analgesia; however, its analgesic effect and optimal timing for its standard use remain unclear. Our study aimed to evaluate the analgesic effect and optimal timing of IV acetaminophen administration in pediatric and adolescent patients undergoing PSF and requiring adequate pain control. Methods: This prospective, randomized, triple-blind trial was conducted in patients aged 11–20 undergoing PSF. Participants were randomized into three groups: the preemptive group (received...

Clinical Research Article

February 5, 2024


Comparison of effects of telmisartan versus valsartan on post-induction hypotension during noncardiac surgery: a prospective observational study
Chung-Sik Oh, Jun Young Park, Seong-Hyop Kim
Korean J Anesthesiol. 2024;77(3):335-344.

Background: Telmisartan is considered more potent than valsartan. Hemodynamic response during anesthesia induction may be influenced by anti-hypertension (HTN) medication. The present study compared the effect of anti-HTN medications on post-induction hypotension during noncardiac surgeries. Methods: This observational study standardized the anesthetic regimen across patients, with hypotension defined as mean blood pressure (BP) of less than 65 mmHg. The hemodynamic changes within 5 min before and after endotracheal intubation, and within 10 min before and after surgical incision were measured. Transthoracic echocardiographic evaluation of the left ventricle (LV) during anesthesia induction...

Clinical Research Article

March 12, 2024


Efficacy of intraoperative blood salvage and autotransfusion in living-donor liver transplantation: a retrospective cohort study
Jongchan Lee, Sujung Park, Jae Geun Lee, Sungji Choo, Bon-Nyeo Koo
Korean J Anesthesiol. 2024;77(3):345-352.

Background: Liver transplantation (LT) may be associated with massive blood loss and the need for allogeneic blood transfusion. Intraoperative blood salvage autotransfusion (IBSA) can reduce the need for allogeneic blood transfusion. This study aimed to investigate the effectiveness of blood salvage in LT. Methods: Among 355 adult patients who underwent elective living-donor LT between January 1, 2019, and December 31, 2022, 59 recipients without advanced hepatocellular carcinoma received IBSA using Cell Saver (CS group). Based on sex, age, model for end-stage liver disease (MELD) score, preoperative laboratory results, and other factors, 118 of the 296 recipients who did not undergo IBSA were matched using propensity score (non-CS group). The primary outcome...

Clinical Research Article

March 5, 2024


Comparison of lung aeration loss in open abdominal oncologic surgeries after ventilation with electrical impedance tomography-guided PEEP versus conventional PEEP: a pilot feasibility study
A. R. Karthik, Nishkarsh Gupta, Rakesh Garg, Sachidanand Jee Bharati, M. D. Ray, et al.
Korean J Anesthesiol. 2024;77(3):353-363.

Background: Existing literature lacks high-quality evidence regarding the ideal intraoperative positive end-expiratory pressure (PEEP) to minimize postoperative pulmonary complications (PPCs). We hypothesized that applying individualized PEEP derived from electrical impedance tomography would reduce the severity of postoperative lung aeration loss, deterioration in oxygenation, and PPC incidence. Methods: A pilot feasibility study was conducted on 36 patients who underwent open abdominal oncologic surgery. The patients were randomized to receive individualized PEEP or conventional PEEP at 4 cmH2O. The primary outcome was the impact of individualized PEEP on changes in the modified lung...

Clinical Research Article

March 14, 2024


The minimum effective concentration (MEC90) of bupivacaine for an ultrasound-guided suprainguinal fascia iliaca compartment block for analgesia in knee surgery: a dose-finding study
Caner Genc, Serkan Tulgar, Murat Unal, Ahmet Serhat Genc, Lokman Kehribar, et al.
Korean J Anesthesiol. 2024;77(3):364-373.

Background: In recent years, the suprainguinal fascia iliaca compartment block (SFICB) has become more common in clinical practice. This assessor-blinded dose-finding study aimed to determine the minimum effective concentration (MEC90, MEC95) of bupivacaine for a single-injection SFICB in patients undergoing arthroscopic anterior cruciate ligament repair. Methods: This prospective study was conducted at a tertiary hospital (postoperative recovery room and ward). The SFICB was performed as a postsurgical intervention after spinal anesthesia. Seventy patients were allocated using the biased-coin design up-and-down sequential method. The ultrasound-guided...

Clinical Research Article

March 14, 2024


Comparison of analgesic effects between programmed intermittent epidural boluses and continuous epidural infusion after cesarean section: a randomized controlled study
Yu Jeong Bang, Heejoon Jeong, RyungA Kang, Ji-Hee Sung, Suk-Joo Choi, et al.
Korean J Anesthesiol. 2024;77(3):374-383.

Background: This study aimed to compare the analgesic effects of programmed intermittent epidural boluses (PIEB) and continuous epidural infusion (CEI) for postoperative analgesia after elective cesarean section (CS). Methods: Seventy-four women who underwent elective CS were randomized to receive either PIEB or CEI. The PIEB group received 4 ml-intermittent boluses of 0.11% ropivacaine every hour at a rate of 120 ml/h. The CEI group received a constant rate of 4 ml/h of 0.11% ropivacaine. The primary outcome was the pain score at rest at 36 h after CS. Secondary outcomes included...

Experimental Research Article

February 15, 2024


Neuroprotective effect of erythropoietin on anesthesia-induced neurotoxicity through the modulation of autophagy in Caenorhabditis elegans
Bon-Wook Koo, Hyun-Jung Shin, Sooyoung Jeon, Jung Hyun Bang, Sang-Hwan Do, et al.
Korean J Anesthesiol. 2024;77(3):384-391.

Background: The anti-oxidative, anti-inflammatory, and anti-apoptotic effects of erythropoietin may provide neuroprotective effects. Erythropoietin also modulates autophagy signaling that may play a role in anesthesia-induced neurotoxicity (AIN). Herein, we investigated whether AIN can be attenuated by the neuroprotective effect of erythropoietin in the Caenorhabditis elegans (C. elegans). Methods: Synchronized worms were divided into the control, Iso, EPO, and EPO-Iso groups. The chemotaxis index (CI) was evaluated when they reached the young adult stage. The lgg-1::GFP-positive puncta per seam cell were used to determine the autophagic events. The erythropoietin-mediated pathway of autophagy...
Comparison of analgesic effects between programmed intermittent epidural boluses and continuous epidural infusion after cesarean section: a randomized controlled study
Yu Jeong Bang, Heejoon Jeong, RyungA Kang, Ji-Hee Sung, Suk-Joo Choi, Soo-Young Oh, Tae Soo Hahm, Young Hee Shin, Yeon Woo Jeong, Soo Joo Choi, et al.
Korean J Anesthesiol. 2024;77(3):374-383.

Clinical Research Article

March 14, 2024
Association of preoperative blood glucose level with delirium after non-cardiac surgery in diabetic patients
Soo Jung Park, Ah Ran Oh, Jong-Hwan Lee, Kwangmo Yang, Jungchan Park
Korean J Anesthesiol. 2024;77(2):226-235.

Clinical Research Article

January 4, 2024
Perioperative adverse cardiac events and mortality after non-cardiac surgery: a multicenter study
Byungjin Choi, Ah Ran Oh, Jungchan Park, Jong-Hwan Lee, Kwangmo Yang, Dong Yun Lee, Sang Youl Rhee, Sang-Soo Kang, Seung Do Lee, Sun Hack Lee, et al.
Korean J Anesthesiol. 2024;77(1):66-76.

Clinical Research Article

May 10, 2023
Comparison of the pericapsular nerve group block with the intra-articular and quadratus lumborum blocks in primary total hip arthroplasty: a randomized controlled trial[commentary-article]
Tayfun Et, Muhammet Korkusuz
Korean J Anesthesiol. 2023;76(6):575-585.

Clinical Research Article

April 4, 2023
Usefulness of C-curved stylet for intubation with the C-MAC® Miller videolaryngoscope in neonates and infants: a prospective randomized controlled trial[commentary-article]
Jung-Bin Park, Pyo-Yoon Kang, Taeyup Kim, Sang-Hwan Ji, Young-Eun Jang, Eun-Hee Kim, Jin-Tae Kim, Hee-Soo Kim, Ji Hyun Lee
Korean J Anesthesiol. 2023;76(5):433-441.

Clinical Research Article

December 23, 2022
Effect of patient decision aids on choice between sugammadex and neostigmine in surgeries under general anesthesia: a multicenter randomized controlled trial
Li-Kai Wang, Yao-Tsung Lin, Jui-Tai Chen, Winnie Lan, Kuo-Chuan Hung, Jen-Yin Chen, Kuei-Jung Liu, Yu-Chun Yen, Yun-Yun Chou, Yih-Giun Cherng, et al.
Korean J Anesthesiol. 2023;76(4):280-289.

Clinical Research Article

December 5, 2022
Preemptive visceral analgesic effect of thoracic paravertebral block on postoperative opioid consumption in patients undergoing laparoscopic cholecystectomy: a prospective, randomized, assessor-blind study
Jong-Hyuk Lee, Chan-Sik Kim, Hyungtae Kim, Jae Moon Choi, Youngmu Kim, Sung-Moon Jeong, Seong-Soo Choi
Korean J Anesthesiol. 2023;76(3):203-212.

Clinical Research Article

December 21, 2022
Retrospective analysis of the incidence and predictors of postoperative nausea and vomiting after orthopedic surgery under spinal anesthesia
Jae-Woo Ju, Jina Kwon, Seokha Yoo, Ho-Jin Lee
Korean J Anesthesiol. 2023;76(2):99-106.

Clinical Research Article

July 13, 2022
Single-shot regional anesthesia for laparoscopic cholecystectomies: a systematic review and network meta-analysis[commentary-article]
Alessandro De Cassai, Nicolò Sella, Federico Geraldini, Serkan Tulgar, Ali Ahiskalioglu, Burhan Dost, Silvia Manfrin, Yunus Emre Karapinar, Greta Paganini, Muzeyyen Beldagli, et al.
Korean J Anesthesiol. 2023;76(1):34-46.

Clinical Research Article

November 8, 2022
Determination of the 95% effective dose of remimazolam to achieve loss of consciousness during anesthesia induction in different age groups
Juyeon Oh, Sung Yong Park, Sook Young Lee, Ju Yeol Song, Ga Yun Lee, Ji Hyun Park, Han Bum Joe
Korean J Anesthesiol. 2022;75(6):510-517.

Clinical Research Article

August 1, 2022
Prognostic value of left ventricular apical four-chamber longitudinal strain after heart valve surgery in real-world practice
Jae-Sik Nam, Ji-Hyun Chin, Hyun-Uk Kang, Juyoun Kim, Kyoung-Woon Joung, In-Cheol Choi
Korean J Anesthesiol. 2022;75(5):416-426.

Clinical Research Article

June 15, 2022
Video laryngoscope versus USB borescope-aided endotracheal intubation in adults with anticipated difficult airway: a prospective randomized controlled study
Mohamed Elshazly, Mark Medhat, Sahar Marzouk, Enas M. Samir
Korean J Anesthesiol. 2022;75(4):331-337.

Clinical Research Article

May 18, 2022
The effect of ultrasound-guided bilateral thoracic retrolaminar block on analgesia after pediatric open cardiac surgery: a randomized controlled double-blind study
Ibrahim Abdelbaser, Nabil A. Mageed, Sherif I. Elfayoumy, Mohamed Magdy, Mohamed M. Elmorsy, Mahmoud M. ALseoudy
Korean J Anesthesiol. 2022;75(3):276-282.

Clinical Research Article

January 12, 2022
Effect of chemotherapy on effect-site concentration of propofol for loss of consciousness in patients with colorectal cancer
Seunghee Ki, Yongwon Cho, Youngkyung Choi, Sehun Lim, Myounghun Kim, Jeonghan Lee
Korean J Anesthesiol. 2022;75(2):160-167.

Clinical Research Article

September 17, 2021
Effect of postoperative non-steroidal anti-inflammatory drugs on anastomotic leakage after pancreaticoduodenectomy
Susie Yoon, Hyerin Kim, Hye-Yeon Cho, Ho-Jin Lee, Hongbeom Kim, Hyung-Chul Lee, Jin-Young Jang
Korean J Anesthesiol. 2022;75(1):61-70.

Clinical Research Article

May 24, 2021
Analysis of endotracheal intubation-related judicial precedents in South Korea
Hye-Yeon Cho, SuHwan Shin, SangJin Lee, Susie Yoon, Ho-Jin Lee
Korean J Anesthesiol. 2021;74(6):506-513.

Clinical Research Article

March 25, 2021
Explanation of trial sequential analysis: using a post-hoc analysis of meta-analyses published in Korean Journal of Anesthesiology
Alessandro De Cassai, Martina Tassone, Federico Geraldini, Massimo Sergi, Nicolò Sella, Annalisa Boscolo, Marina Munari
Korean J Anesthesiol. 2021;74(5):383-393.

Clinical Research Article

July 20, 2021
Prediction of endotracheal tube size using a printed three-dimensional airway model in pediatric patients with congenital heart disease: a prospective, single-center, single-group study
Seyeon Park, Jisoo Ahn, Sung Uk Yoon, Ki Seok Choo, Hye-Jin Kim, Minwoo Chung, Hee Young Kim
Korean J Anesthesiol. 2021;74(4):333-341.

Clinical Research Article

May 31, 2021
Comparison between two different concentrations of a fixed dose of ropivacaine in interscalene brachial plexus block for pain management after arthroscopic shoulder surgery: a randomized clinical trial
Seung Cheol Lee, Joon Ho Jeong, Seong Yeop Jeong, Sung Wan Kim, Chan Jong Chung, So Ron Choi, Jeong Ho Kim, Sang Yoong Park
Korean J Anesthesiol. 2021;74(3):226-233.

Clinical Research Article

August 21, 2020
Four different methods of measuring cardiac index during cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
Amon Heijne, Piet Krijtenburg, Andre Bremers, Gert Jan Scheffer, Ignacio Malagon, Cornelis Slagt
Korean J Anesthesiol. 2021;74(2):120-133.

Clinical Research Article

August 21, 2020
Demographic and clinical factors associated with same-day discharge and unplanned readmission following shoulder arthroplasty: a retrospective cohort study
Brittany N. Burton, John J. Finneran, Aaron Angerstein, Evelyn Ross, Ana Mitchell, Ruth S. Waterman, Ahmad Elsharydah, Engy T. Said, Rodney A. Gabriel
Korean J Anesthesiol. 2021;74(1):30-37.

Clinical Research Article

March 12, 2020
Effects of hypercarbia on arterial oxygenation during one-lung ventilation: prospective randomized crossover study
Junho Lee, Yesull Kim, Juhan Mun, Joseph Lee, Seonghoon Ko
Korean J Anesthesiol. 2020;73(6):534-541.

Clinical Research Article

May 28, 2020
Randomized, controlled trial comparing respiratory and analgesic effects of interscalene, anterior suprascapular, and posterior suprascapular nerve blocks for arthroscopic shoulder surgery
Yean Chin Lim, Zhao Kun Koo, Vivian. W. Ho, See Seong Chang, Shivani Manohara, Qian Jun Tong
Korean J Anesthesiol. 2020;73(5):408-416.

Clinical Research Article

July 16, 2020
Influence of alcohol consumption on blood coagulation in rotational thromboelastometry (ROTEM): an in-vivo study
Hendrik Eismann, Lion Sieg, Hala Ahmed, Joerg Teske, Patrick Behrendt, Lars Friedrich, Carsten Schumacher, Kai Johanning
Korean J Anesthesiol. 2020;73(4):334-341.

Experimental Research Article

April 16, 2020
Whole-blood hypocoagulable profile correlates with a greater risk of death within 28 days in patients with severe sepsis
Annalisa Boscolo, Luca Spiezia, Elena Campello, Diana Bertini, Vittorio Lucchetta, Eleonora Piasentini, Alessandro De Cassai, Paolo Simioni
Korean J Anesthesiol. 2020;73(3):224-231.

Clinical Research Article

January 7, 2020
Neuromuscular blockade reversal with sugammadex versus pyridostigmine/ glycopyrrolate in laparoscopic cholecystectomy: a randomized trial of effects on postoperative gastrointestinal motility
Jihyun An, Heeyun Noh, Eunju Kim, Jihyang Lee, Kyeongyoon Woo, Hyunkyum Kim
Korean J Anesthesiol. 2020;73(2):137-144.

Clinical Research Article

October 22, 2019
Effect of anesthetic method on incidence of delirium after total hip replacement arthroplasty in South Korea: a population-based study using National Health Insurance claims data
Eun-Ji Choi, Yoon Ji Choi, Sang Won Lee, Yun-Mi Choi, Hyun-Su Ri, Ju Yeon Park, Soon Ji Park, Jung-Min Son, Yoon Sook Lee
Korean J Anesthesiol. 2020;73(1):36-43.

Clinical Research Article

August 3, 2019
Comparison of clinical performance of i-gelⓇ and Baska MaskⓇ during laparoscopic cholecystectomy
So Ron Choi, Tae Young Lee, Sung Wan Kim, Sang Yoong Park, Chan Jong Chung, Jeong Ho Kim
Korean J Anesthesiol. 2019;72(6):576-582.

Special Issue: Airway Management

Clinical Research Article

August 20, 2019
Programmed intermittent epidural bolus as compared to continuous epidural infusion for the maintenance of labor analgesia: a prospective randomized single-blinded controlled trial
Christina W. Fidkowski, Sonalee Shah, Mohamed-Rida Alsaden
Korean J Anesthesiol. 2019;72(5):472-478.

Clinical Research Article

June 20, 2019
The analgesic efficacy of the transversalis fascia plane block in iliac crest bone graft harvesting: a randomized controlled trial
Nicholas D. Black, Laith Malhas, Rongyu Jin, Anuj Bhatia, Vincent W. S. Chan, Ki Jinn Chin
Korean J Anesthesiol. 2019;72(4):336-343.

Clinical Research Article

March 19, 2019
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  • Sudden ventricular fibrillation due to absence of pericardium in left upper lobectomy -a case report-. Korean J Anesthesiol. 2024;77:401-404
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