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Comparison of the pericapsular nerve group block with the intra-articular and quadratus lumborum blocks in primary total hip arthroplasty: a randomized controlled trial
Tayfun Et, Muhammet Korkusuz
Korean J Anesthesiol. 2023;76(6):575-585.

Review Article

April 19, 2023


Pediatric perioperative fluid management
Hyungmook Lee, Jin Tae Kim
Korean J Anesthesiol. 2023;76(6):519-530.

The purpose of perioperative fluid management in children is to maintain adequate volume status, electrolyte level, and endocrine system homeostasis during the perioperative period. Although hypotonic solutions containing glucose have traditionally been used as pediatric maintenance fluids, recent studies have shown that isotonic balanced crystalloid solutions lower the risk of hyponatremia and metabolic acidosis perioperatively. Isotonic balanced solutions have been found to exhibit safer and more physiologically appropriate characteristics for perioperative fluid maintenance and replacement. Additionally, adding 1–2.5% glucose to the maintenance fluid can help prevent children from developing hypoglycemia as well as lipid mobilization, ketosis, and hyperglycemia. The fasting time should be as short as possible without compromising safety;...

Statistical Round

November 14, 2023


Intention-to-treat versus as-treated versus per-protocol approaches to analysis
EunJin Ahn, Hyun Kang
Korean J Anesthesiol. 2023;76(6):531-539.

Randomized controlled trials (RCTs) are considered the most rigorous study design for testing hypotheses and the gold standard for evaluating intervention effectiveness. However, RCTs are often conducted under the assumption of ideal conditions that may differ from real-world scenarios in which various issues, such as loss to follow-up, mistakes in participant enrollment or intervention, and low subject compliance or adherence, may occur. There are various group-defining strategies for analyzing RCT data, including the intention-to-treat (ITT), as-treated, and per-protocol (PP) approaches. The ITT principle involves analyzing all participants according to their initial group assignments, regardless of study completion and compliance or adherence to treatment protocols. This approach aims to replicate real-world...

Clinical Research Article

September 26, 2023


Predicting optimal endotracheal tube size and depth in pediatric patients using demographic data and machine learning techniques
Hyeonsik Kim, Hyun-Kyu Yoon, Hyeonhoon Lee, Chul-Woo Jung, Hyung-Chul Lee
Korean J Anesthesiol. 2023;76(6):540-549.

Background: Use of endotracheal tubes (ETTs) with appropriate size and depth can help minimize intubation-related complications in pediatric patients. Existing age-based formulae for selecting the optimal ETT size present several inaccuracies. We developed a machine learning model that predicts the optimal size and depth of ETTs in pediatric patients using demographic data, enabling clinical applications. Methods: Data from 37,057 patients younger than 12 years who underwent general anesthesia with endotracheal intubation were retrospectively analyzed. Gradient boosted regression tree (GBRT) model was developed and compared with traditional age-based formulae. Results: The...

Clinical Research Article

February 24, 2023


Association between inflammation-based prognostic markers and mortality of non-cardiac surgery
Ah Ran Oh, Jungchan Park, Jong-Hwan Lee, Kwangmo Yang, Joonghyun Ahn, et al.
Korean J Anesthesiol. 2023;76(6):550-558.

Background: To evaluate the association between inflammation and nutrition-based biomarkers and postoperative outcomes after non-cardiac surgery. Methods: Between January 2011 and June 2019, a total of 102,052 patients undergoing non-cardiac surgery were evaluated, with C-reactive protein (CRP), albumin, and complete blood count (CBC) measured within six months before surgery. We assessed their CRP-to-albumin ratio (CAR), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and modified Glasgow Prognostic Score (mGPS). We determined the best cut-off values by using the receiver operating characteristic (ROC) curves. Patients were divided into high and low groups according to the estimated threshold, and we compared the one-year mortality. Results: The one-year mortality of the entire sample was 4.2%. ROC analysis...

Clinical Research Article

April 24, 2023


Does intravenous patient-controlled analgesia or continuous block prevent rebound pain following infraclavicular brachial plexus block after distal radius fracture fixation? A prospective randomized controlled trial
Jong-hyuk Lee, Ha-jung Kim, Jae Kwang Kim, Sungjoo Cheon, Young Ho Shin
Korean J Anesthesiol. 2023;76(6):559-566.

Background: The purpose of this study was to investigate the role of opioid-based intravenous patient-controlled analgesia (IV PCA) or continuous brachial plexus block (BPB) in controlling rebound pain after distal radius fracture (DRF) fixation under BPB as well as total opioid consumption. Methods: A total of 66 patients undergoing surgical treatment for a displaced DRF with volar plate fixation were randomized to receive a single infraclavicular BPB (BPB only group) (n = 22), a single infraclavicular BPB with IV PCA (IV PCA group) (n = 22), or a single infraclavicular...

Clinical Research Article

May 10, 2023


Quality of recovery in hospital and disability-free survival at three months after major abdominal surgery
Yuki Kinugasa, Mitsuru Ida, Shohei Nakatani, Kayo Uyama, Masahiko Kawaguchi
Korean J Anesthesiol. 2023;76(6):567-574.

Background: The Quality of Recovery-15 (QoR-15) and 12-item World Health Organization Disability Assessment Schedule 2.0 scales are post-surgery patient-reported outcome measures. We aimed to evaluate the association between immediate in-hospital postoperative recovery and mid-term disability-free survival (DFS) after discharge. Methods: We conducted a prospective observational study at a university hospital and enrolled 260 patients aged ≥ 65 years with cancer who were undergoing elective major abdominal surgery. The association between poor postoperative recovery, defined as a QoR-15 score < 90 on postoperative day (POD) 2, and the DFS three months later was assessed using Fisher’s exact test. The odds ratio of poor recovery on POD 2 to DFS was calculated using...

Clinical Research Article

April 4, 2023


Comparison of the pericapsular nerve group block with the intra-articular and quadratus lumborum blocks in primary total hip arthroplasty: a randomized controlled trial
Tayfun Et, Muhammet Korkusuz
Korean J Anesthesiol. 2023;76(6):575-585.

Background: The pericapsular nerve group (PENG) block, quadratus lumborum block (QLB), and intra-articular (IA) local anesthetic injection have been shown to provide effective analgesia in total hip arthroplasty (THA). This randomized study aimed to compare the analgesic efficacy, motor protection, and quality of recovery associated with the PENG block, QLB, and IA injection. Methods: Eighty-nine patients who underwent a unilateral primary THA under spinal anesthesia were randomly assigned to the PENG (n=30), QLB (n=30), or IA (n=29) group. The primary outcome was the numerical rating scale (NRS) score over the first...

Clinical Research Article

March 16, 2023


Effects of dexmedetomidine on pulmonary function in patients receiving one-lung ventilation: a meta-analysis of randomized controlled trial
Lin Yang, Yongheng Cai, Lin Dan, He Huang, Bing Chen
Korean J Anesthesiol. 2023;76(6):586-596.

Background: Mechanical ventilation, particularly one-lung ventilation (OLV), can cause pulmonary dysfunction. This meta-analysis assessed the effects of dexmedetomidine on the pulmonary function of patients receiving OLV. Methods: The Embase, PubMed, MEDLINE, Cochrane Library, ClinicalTrials.gov, and Chinese Clinical Trial Registry databases were systematically searched. The primary outcome was oxygenation index (OI). Other outcomes including the incidence of postoperative complications were assessed. Results: Fourteen randomized controlled trials involving 845 patients were included in this meta-analysis. Dexmedetomidine improved the OI at 30 (mean difference [MD]: 40.49, 95% CI [10.21, 70.78]), 60 (MD: 60.86,...

Clinical Research Article

April 17, 2023


Comparison of different nonsteroidal anti-inflammatory drugs for cesarean section: a systematic review and network meta-analysis
Iona Murdoch, Anthony L Carver, Pervez Sultan, James E O’Carroll, Lindsay Blake, et al.
Korean J Anesthesiol. 2023;76(6):597-616.

Background: Cesarean section is associated with moderate to severe pain and nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly employed. The optimal NSAID, however, has not been elucidated. In this network meta-analysis and systematic review, we compared the influence of control and individual NSAIDs on the indices of analgesia, side effects, and quality of recovery. Methods: CDSR, CINAHL, CRCT, Embase, LILACS, PubMed, and Web of Science were searched for randomized controlled trials comparing a specific NSAID to either control or another NSAID in elective or emergency cesarean section under general or neuraxial anesthesia. Network plots and league tables were constructed, and the quality of evidence was evaluated with Grading of Recommendations Assessment, Development...

Clinical Research Article

December 21, 2022


Effect of magnesium sulfate on oxygenation and lung mechanics in morbidly obese patients undergoing bariatric surgery: a prospective double-blind randomized clinical trial
Marwa M. Mowafi, Marwa A. K. Elbeialy, Rasha Gamal Abusinna
Korean J Anesthesiol. 2023;76(6):617-626.

Background: Respiratory mechanics are often significantly altered in morbidly obese patients and magnesium sulfate (MgSO4) is a promising agent for managing several respiratory disorders. This study aimed to examine the effects of MgSO4 infusions on arterial oxygenation and lung mechanics in patients with morbid obesity undergoing laparoscopic bariatric surgery. Methods: Forty patients with morbid obesity aged 21–60 years scheduled for laparoscopic bariatric surgery under general anesthesia were randomly allocated to either the control (normal saline infusion) or MgSO4 group (30 mg/kg lean body weight [LBW] of...

Experimental Research Article

August 21, 2023


Effects of sevoflurane on metalloproteinase and natural killer group 2, member D (NKG2D) ligand expression and natural killer cell-mediated cytotoxicity in breast cancer: an in vitro study
Hyae Jin Kim, Soeun Jeon, Hyeon Jeong Lee, Jaeho Bae, Hyun-Su Ri, et al.
Korean J Anesthesiol. 2023;76(6):627-639.

Background: We investigated the effects of sevoflurane exposure on the expression of matrix metalloproteinase (MMP), expression and ablation of natural killer group 2, member D (NKG2D) ligands (UL16-binding proteins 1–3 and major histocompatibility complex class I chain-related molecules A/B), and natural killer (NK) cell-mediated cytotoxicity in breast cancer cells. Methods: Three human breast cancer cell lines (MCF-7, MDA-MB-453, and HCC-70) were incubated with 0 (control), 600 (S6), or 1200 μM (S12) sevoflurane for 4 h. The gene expression of NKG2D ligands and their protein expression on cancer cell surfaces were measured...
Receiver operating characteristic curve: overview and practical use for clinicians
Francis Sahngun Nahm
Korean J Anesthesiol. 2022;75(1):25-36.

Statistical Round

January 18, 2022
Considerations for crossover design in clinical study
Chi-Yeon Lim, Junyong In
Korean J Anesthesiol. 2021;74(4):293-299.

Statistical Round

July 30, 2021
Remimazolam – current knowledge on a new intravenous benzodiazepine anesthetic agent
Seong-Hyop Kim, Jörg Fechner
Korean J Anesthesiol. 2022;75(4):307-315.

Review Article

May 19, 2022
Local anesthetic systemic toxicity of levobupivacaine in erector spinae plane block
Shunsuke Yawata, Noritaka Imamachi, Shinichi Sakura, Hanako Yamamoto, Yoji Saito
Korean J Anesthesiol. 2021;74(3):271-272.

Letter to the Editor

October 26, 2020
The role of rotational thromboelastometry during the COVID-19 pandemic: a narrative review
Klaus Görlinger, Hawra Almutawah, Fatimah Almutawaa, Maryam Alwabari, Zahra Alsultan, Jumanah Almajed, Mahmoud Alwabari, Maryam Alsultan, Duri Shahwar, Khaled Ahmed Yassen
Korean J Anesthesiol. 2021;74(2):91-102.

Review Article

January 13, 2021
Trial sequential analysis: plain and simple
Alessandro De Cassai, Laura Pasin, Annalisa Boscolo, Michele Salvagno, Paolo Navalesi
Korean J Anesthesiol. 2021;74(4):363-365.

Letter to the Editor

December 18, 2020
General considerations for sample size estimation in animal study
Mun Jung Ko, Chi-Yeon Lim
Korean J Anesthesiol. 2021;74(1):23-29.

Statistical Round

January 26, 2021
Demographic and clinical factors associated with same-day discharge and unplanned readmission following shoulder arthroplasty: a retrospective cohort study
Brittany N. Burton, John J. Finneran, Aaron Angerstein, Evelyn Ross, Ana Mitchell, Ruth S. Waterman, Ahmad Elsharydah, Engy T. Said, Rodney A. Gabriel
Korean J Anesthesiol. 2021;74(1):30-37.

Clinical Research Article

March 12, 2020
Effectiveness of four ultrasonographic parameters as predictors of difficult intubation in patients without anticipated difficult airway
Rishabh Agarwal, Gaurav Jain, Ankit Agarwal, Nishith Govil
Korean J Anesthesiol. 2021;74(2):134-141.

Clinical Research Article

June 15, 2020
Postoperative neurocognitive disorders
Setayesh Reza Tasbihgou, Anthony Ray Absalom
Korean J Anesthesiol. 2021;74(1):15-22.

Review Article

July 6, 2020
Validity and reliability of the Korean version of the Quality of Recovery-15 questionnaire
Jun Ho Lee, Minjong Ki, Seungseo Choi, Cheol Jong Woo, Deokkyu Kim, Hyungsun Lim, Dong-Chan Kim
Korean J Anesthesiol. 2021;74(2):142-149.

Clinical Research Article

October 30, 2020
Neuromuscular blockade management in patients with COVID-19
Harold Chaves-Cardona, Vivian Hernandez-Torres, Sean Kiley, Johnathan Renew
Korean J Anesthesiol. 2021;74(4):285-292.

Review Article

May 3, 2021
Effect of preoperative dexmedetomidine nebulization on the hemodynamic response to laryngoscopy and intubation: a randomized control trial
Satyajeet Misra, Bikram Kishore Behera, Jayanta Kumar Mitra, Alok Kumar Sahoo, Sritam Swarup Jena, Anand Srinivasan
Korean J Anesthesiol. 2021;74(2):150-157.

Clinical Research Article

May 20, 2020
Pulmonary vasculature in COVID-19: mechanism to monitoring!
Rohan Magoon
Korean J Anesthesiol. 2021;74(2):186-187.

Letter to the Editor

October 5, 2020
Concepts and emerging issues of network meta-analysis
EunJin Ahn, Hyun Kang
Korean J Anesthesiol. 2021;74(5):371-382.

Review Article

September 23, 2021
Delayed recurrent spontaneous pneumothorax in a patient recovering from COVID-19 pneumonia
Viraj Shah, Katie Brill, Gunmeet Dhingra, Santhana Kannan
Korean J Anesthesiol. 2021;74(2):183-185.

Letter to the Editor

September 1, 2020
Prediction of endotracheal tube size using a printed three-dimensional airway model in pediatric patients with congenital heart disease: a prospective, single-center, single-group study
Seyeon Park, Jisoo Ahn, Sung Uk Yoon, Ki Seok Choo, Hye-Jin Kim, Minwoo Chung, Hee Young Kim
Korean J Anesthesiol. 2021;74(4):333-341.

Clinical Research Article

May 31, 2021
Anatomical classification and clinical application of thoracic paraspinal blocks
Shin Hyung Kim
Korean J Anesthesiol. 2022;75(4):295-306.

Review Article

April 4, 2022
Risk factors associated with hypotensive bradycardic events during open shoulder surgery in the beach chair position
Ji Won Choi, Duk Kyung Kim, Hee Joon Jeong, Young Ri Kim, Yoon Joo Chung, Yong Hun Son
Korean J Anesthesiol. 2021;74(1):38-44.

Clinical Research Article

February 4, 2020
Anesthetics or anesthetic techniques and cancer surgical outcomes: a possible link
Azeem Alam, Sanketh Rampes, Sonam Patel, Zac Hana, Daqing Ma
Korean J Anesthesiol. 2021;74(3):191-203.

Review Article

February 17, 2021
Regional analgesia techniques for video-assisted thoracic surgery: a frequentist network meta-analysis
Yumin Jo, Seyeon Park, Chahyun Oh, Yujin Pak, Kuhee Jeong, Sangwon Yun, Chan Noh, Woosuk Chung, Yoon-Hee Kim, Young Kwon Ko, et al.
Korean J Anesthesiol. 2022;75(3):231-244.

Clinical Research Article

October 13, 2021
The effect of ultrasound-guided bilateral thoracic retrolaminar block on analgesia after pediatric open cardiac surgery: a randomized controlled double-blind study
Ibrahim Abdelbaser, Nabil A. Mageed, Sherif I. Elfayoumy, Mohamed Magdy, Mohamed M. Elmorsy, Mahmoud M. ALseoudy
Korean J Anesthesiol. 2022;75(3):276-282.

Clinical Research Article

January 12, 2022
Cadaveric investigation of the spread of the thoracoabdominal nerve block using the perichondral and modified perichondral approaches
Bahadir Ciftci, Haci Ahmet Alici, Gamze Ansen, Bayram Ufuk Sakul, Serkan Tulgar
Korean J Anesthesiol. 2022;75(4):357-359.

Letter to the Editor

April 26, 2022
Hyper- and hypocoagulability in COVID-19 as assessed by thromboelastometry -two case reports-
Robert Kong, Nevil Hutchinson, Klaus Görlinger
Korean J Anesthesiol. 2021;74(4):350-354.

Case Report

August 10, 2020
Effect of single dose preoperative intravenous ibuprofen on postoperative pain and opioid consumption: a systematic review and meta-analysis
Su Yeon Kim, Sangseok Lee, Yeji Lee, Hyunho Kim, Kye-Min Kim
Korean J Anesthesiol. 2021;74(5):409-421.

Clinical Research Article

February 22, 2021
The effect of interscalene brachial plexus block with propofol sedation on preventing perioperative hypothermia during arthroscopic shoulder surgery
Ji Hye Lee, Hyun Joo Heo, Yu Yil Kim, Seung Min Baek, Ki Man Kim, Da Wa Jung
Korean J Anesthesiol. 2021;74(1):53-58.

Clinical Research Article

June 5, 2020
Continuous peripheral nerve blocks compared to thoracic epidurals or multimodal analgesia for midline laparotomy: a systematic review and meta-analysis
Jonathan G. Bailey, Catherine W Morgan, Russell Christie, Janny Xue Chen Ke, M. Kwesi Kwofie, Vishal Uppal
Korean J Anesthesiol. 2021;74(5):394-408.

Clinical Research Article

September 23, 2020
Comeback of ketamine: resurfacing facts and dispelling myths
Abhijit Kumar, Amit Kohli
Korean J Anesthesiol. 2021;74(2):103-114.

Review Article

January 11, 2021
Self-learning software tools for data analysis in meta-analysis
Thrivikrama Padur Tantry, Harish Karanth, Pramal Karkala Shetty, Dinesh Kadam
Korean J Anesthesiol. 2021;74(5):459-461.

Letter to the Editor

March 8, 2021
Mechanisms underlying lipid emulsion resuscitation for drug toxicity: a narrative review
Soo Hee Lee, Ju-Tae Sohn
Korean J Anesthesiol. 2023;76(3):171-182.

Review Article

January 26, 2023
  • Journal Impact Factor 2.9
  • SCImago Journal & Country Rank
  • Hemodynamic management during off-pump coronary artery bypass surgery: a narrative review of proper targets for safe execution and troubleshooting. Korean J Anesthesiol. 2023;76:267-279
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