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Effect of remimazolam on postoperative delirium and cognitive function in adults undergoing general anesthesia or procedural sedation: a meta-analysis of randomized controlled trials
Ji-In Park, Hyo-Seok Na, Ji-Na Kim, Jung-Hee Ryu, Howon Jang, et al.
Korean J Anesthesiol. 2025;78(2):118-128.

Review Article

December 16, 2024


A comprehensive analysis of propofol abuse, addiction and neuropharmacological aspects: an updated review
Tayfun Uzbay, Andleeb Shahzadi
Korean J Anesthesiol. 2025;78(2):91-104.

This review aims to assess the existing studies on propofol, a relatively new intravenous anesthetic, related to its abuse and addictive potential and to explain the neurobiological and neuropharmacological aspects of propofol addiction. Several neurobiological factors related to complex processes in the brain influence propofol abuse and addiction. In this review, we assessed the literature regarding propofol abuse and addiction, including both experimental and clinical studies. We selected articles from animal studies, case reports, clinical trials, meta-analyses, narrative reviews, and systematic reviews to extract all relevant crucial quantitative data with a measure of neurobiological and neuropharmacological aspects. Thus, the main goal of this study was to investigate the current literature...

Review Article

January 15, 2025


Extended reality in anesthesia: a narrative review
Sung Hee Han, Kristen L Kiroff, Sakura Kinjo
Korean J Anesthesiol. 2025;78(2):105-117.

The application of extended reality (XR) technology is rapidly expanding in the medical field, including anesthesia. This review aims to introduce the current literature on XR utilization to help anesthesiologists adopt this technology in education and clinical practice. XR is useful for both knowledge acquisition and skill training in a wide range of settings, from students to medical professionals. One of its major benefits is harm reduction through simulation scenarios that allow for immersion in clinical situations and opportunities to practice procedures and tasks. These scenarios often involve both technical and non-technical skills, enabling clinicians to enhance their capabilities without risking patient safety. In clinical settings, XR can also be...

Clinical Research Article

January 3, 2025


Effect of remimazolam on postoperative delirium and cognitive function in adults undergoing general anesthesia or procedural sedation: a meta-analysis of randomized controlled trials
Ji-In Park, Hyo-Seok Na, Ji-Na Kim, Jung-Hee Ryu, Howon Jang, et al.
Korean J Anesthesiol. 2025;78(2):118-128.

Background: Remimazolam is a novel short-acting benzodiazepine. This study compared the effects of remimazolam and propofol on cognitive function in adult patients after surgery or other procedures. Methods: We searched electronic databases, including PubMed, Embase, CENTRAL, Web of Science, and Scopus, for relevant studies. The primary outcome was the proportion of participants who experienced delirium or impaired cognitive function postoperatively. Secondary outcomes included the incidence of hypotension, bradycardia, and postoperative nausea and vomiting. We estimated the odds ratios (OR) and mean differences (MD) with 95% CIs using a random-effects model. Results: In...

Clinical Research Article

December 20, 2024


Post-anesthesia care unit delirium in children with moyamoya disease undergoing indirect revascularization: incidence and risk factors
Kun Liu, Lin He
Korean J Anesthesiol. 2025;78(2):129-138.

Background: Delirium in the post-anesthesia care unit (PACU) may be associated with worse outcomes in children with moyamoya disease (MMD). This retrospective study aimed to describe the prevalence of PACU delirium in children with MMD and investigate its risk factors. Methods: Patients with MMD aged < 15 years who underwent indirect revascularization between January 2014 and October 2023 were included in this study. Delirium was assessed using the Pediatric Anesthesia Emergence Delirium Scale. Potential risk factors for PACU delirium were evaluated using multivariate logistic regression. Results: PACU delirium occurred in 245 (33%)...

Clinical Research Article

January 3, 2025


Hypotension after induction of anesthesia with remimazolam or etomidate: a non-inferiority randomized controlled trial in patients undergoing coronary artery bypass grafting
Jeong-Jin Min, Eun Jung Oh, Hyun Ji Hwang, Sungwoo Jo, Hyunsung Cho, et al.
Korean J Anesthesiol. 2025;78(2):139-147.

Background: Remimazolam is a novel ultra-short-acting benzodiazepine known for its hemodynamic stability over propofol. However, its hemodynamic effects compared to those of etomidate are not well established. This study aimed to determine whether the use of remimazolam is non-inferior to etomidate with regard to the occurrence of post-induction hypotension in patients undergoing coronary artery bypass grafting. Methods: Patients were randomly assigned to either the remimazolam group (6 mg/kg/h) or the etomidate group (0.3 mg/kg) for induction of anesthesia. Anesthetic depth was adjusted based on the bispectral index. Primary outcome was the...

Clinical Research Article

January 23, 2025


Effect of remimazolam on intraoperative hemodynamic stability in patients undergoing cerebrovascular bypass surgery: a prospective randomized controlled trial
Chang-Hoon Koo, Si Un Lee, Hyeong-Geun Kim, Soowon Lee, Yu Kyung Bae, et al.
Korean J Anesthesiol. 2025;78(2):148-158.

Background: Maintenance of stable blood pressure (BP) during cerebrovascular bypass surgery is crucial to prevent cerebral ischemia. We compared the effect of remimazolam anesthesia with that of propofol-induced and desflurane-maintained anesthesia on intraoperative hemodynamic stability and the need for vasoactive agents in patients undergoing cerebrovascular bypass surgery. Methods: Sixty-five patients were randomized into remimazolam (n = 31, remimazolam-based intravenous anesthesia) and control groups (n = 34, propofol-induced and desflurane-maintained anesthesia). The primary outcome was the occurrence of intraoperative hypotension. The secondary outcomes included hypotension duration, lowest mean BP (MBP), generalized average...

Clinical Research Article

January 21, 2025


Analgesic efficacy of the external oblique intercostal fascial plane block on postoperative acute pain in laparoscopic sleeve gastrectomy: a randomized controlled trial
Elif Sarikaya Ozel, Cengiz Kaya, Esra Turunc, Yasemin B. Ustun, Halil Cebeci, et al.
Korean J Anesthesiol. 2025;78(2):159-170.

Background: Laparoscopic sleeve gastrectomy (LSG) causes significant postoperative pain, necessitating effective multimodal analgesia strategies. This study evaluated the efficacy of the external oblique intercostal block (EOIB) in this context. Methods: This prospective, randomized, controlled, single-blind study conducted between April and December 2023 included 60 patients who underwent LSG. Patients were divided into the EOIB (30 ml 0.25% bupivacaine/side) and control (no block) groups. The primary outcome was the cumulative intravenous morphine milligram equivalent (MME) consumption in the first 24 h postoperatively. Secondary outcomes included 12-h MME consumption, pain scores, intraoperative remifentanil...
Mechanisms underlying lipid emulsion resuscitation for drug toxicity: a narrative review
Soo Hee Lee, Ju-Tae Sohn
Korean J Anesthesiol. 2023;76(3):171-182.

Review Article

January 26, 2023
Intention-to-treat versus as-treated versus per-protocol approaches to analysis
EunJin Ahn, Hyun Kang
Korean J Anesthesiol. 2023;76(6):531-539.

Statistical Round

November 14, 2023
Comparison of postoperative nausea and vomiting between remimazolam and propofol: a propensity score-matched, retrospective, observational, single-center cohort study
Yuji Suzuki, Shingo Kawashima, Hiroshi Makino, Matsuyuki Doi, Yoshiki Nakajima
Korean J Anesthesiol. 2023;76(2):143-151.

Clinical Research Article

October 17, 2022
Role of carotid corrected flow time and peak velocity variation in predicting fluid responsiveness: a systematic review and meta-analysis
Deepak Singla, Bhavna Gupta, Pragya Varshney, Mishu Mangla, Beeraling Ningappa Walikar, Tiajem Jamir
Korean J Anesthesiol. 2023;76(3):183-193.

Clinical Research Article

November 15, 2022
Safety considerations with the current ambulatory trends: more complicated procedures and more complicated patients
Steven Young, Brian Osman, Fred E. Shapiro
Korean J Anesthesiol. 2023;76(5):400-412.

Review Article

March 10, 2023
Single-shot regional anesthesia for laparoscopic cholecystectomies: a systematic review and network meta-analysis[commentary-article]
Alessandro De Cassai, Nicolò Sella, Federico Geraldini, Serkan Tulgar, Ali Ahiskalioglu, Burhan Dost, Silvia Manfrin, Yunus Emre Karapinar, Greta Paganini, Muzeyyen Beldagli, et al.
Korean J Anesthesiol. 2023;76(1):34-46.

Clinical Research Article

November 8, 2022
Surgical pleth index monitoring in perioperative pain management: usefulness and limitations
Seok Kyeong Oh, Young Ju Won, Byung Gun Lim
Korean J Anesthesiol. 2024;77(1):31-45.

Review Article

March 17, 2023
Comparison of the pericapsular nerve group block with the intra-articular and quadratus lumborum blocks in primary total hip arthroplasty: a randomized controlled trial[commentary-article]
Tayfun Et, Muhammet Korkusuz
Korean J Anesthesiol. 2023;76(6):575-585.

Clinical Research Article

April 4, 2023
Comparison of the median and intermediate approaches to the ultrasound-guided sacral erector spinae plane block: a cadaveric and radiologic study
Bilge Olgun Keleş, Necati Salman, Elvan Tekir Yılmaz, Habip Resul Birinci, Alparslan Apan, Selami İnce, Ali Faruk Özyaşar, Aysun Uz
Korean J Anesthesiol. 2024;77(1):156-163.

Experimental Research Article

November 15, 2023
Virtual reality simulator’s effectiveness on the spine procedure education for trainee: a randomized controlled trial
Ji Yeong Kim, Jong Seok Lee, Jae Hee Lee, Yoon Sun Park, Jaein Cho, Jae Chul Koh
Korean J Anesthesiol. 2023;76(3):213-226.

Clinical Research Article

November 2, 2022
Erector spinae plane versus fascia iliaca block after total hip arthroplasty: a randomized clinical trial comparing analgesic effectiveness and motor block
Edoardo Flaviano, Silvia Bettinelli, Maddalena Assandri, Hassam Muhammad, Alberto Benigni, Gianluca Cappelleri, Edward Rivera Mariano, Luca Ferdinando Lorini, Dario Bugada
Korean J Anesthesiol. 2023;76(4):326-335.

Clinical Research Article

January 12, 2023
Ultrasound-guided lumbar erector spinae plane block versus caudal block for postoperative analgesia in pediatric hip and proximal femur surgery: a randomized controlled study
Mohamed Elshazly, AbdelKhalek Shaban, Nevine Gouda, Mahitab Rashad, Sherif M. Soaida
Korean J Anesthesiol. 2023;76(3):194-202.

Clinical Research Article

October 24, 2022
Ramped versus sniffing position in the videolaryngoscopy-guided tracheal intubation of morbidly obese patients: a prospective randomized study
Seongheon Lee, Eun-A Jang, Minjae Hong, Hong-Beom Bae, Joungmin Kim
Korean J Anesthesiol. 2023;76(1):47-55.

Clinical Research Article

August 1, 2022
Effect of total intravenous versus inhalation anesthesia on long-term oncological outcomes in patients undergoing curative resection for early-stage non-small cell lung cancer: a retrospective cohort study[commentary-article]
Kwon Hui Seo, Ji Hyung Hong, Mi Hyoung Moon, Wonjung Hwang, Sea-Won Lee, Jin Young Chon, Hyejin Kwon, Sook Hee Hong, Sukil Kim
Korean J Anesthesiol. 2023;76(4):336-347.

Clinical Research Article

December 28, 2022
Cardiac arrest due to coronary vasospasm after sugammadex administration -a case report-[commentary-article]
Ki Yung Boo, Sang Hyun Park, Sun Kyung Park, Changrock Na, Hyun Jung Kim
Korean J Anesthesiol. 2023;76(1):72-76.

Case Report

August 18, 2022
Preemptive visceral analgesic effect of thoracic paravertebral block on postoperative opioid consumption in patients undergoing laparoscopic cholecystectomy: a prospective, randomized, assessor-blind study
Jong-Hyuk Lee, Chan-Sik Kim, Hyungtae Kim, Jae Moon Choi, Youngmu Kim, Sung-Moon Jeong, Seong-Soo Choi
Korean J Anesthesiol. 2023;76(3):203-212.

Clinical Research Article

December 21, 2022
Dexpanthenol protects against lipopolysaccharide-induced acute kidney injury by restoring aquaporin-2 levels via regulation of the silent information regulator 1 signaling pathway
Eyyüp Sabri Özden, Halil Aşcı, Halil İbrahim Büyükbayram, Mehmet Abdulkadir Sevük, Orhan Berk İmeci, Hatice Kübra Doğan, Özlem Özmen
Korean J Anesthesiol. 2023;76(5):501-509.

Experimental Research Article

May 26, 2023
Association of preoperative blood glucose level with delirium after non-cardiac surgery in diabetic patients
Soo Jung Park, Ah Ran Oh, Jong-Hwan Lee, Kwangmo Yang, Jungchan Park
Korean J Anesthesiol. 2024;77(2):226-235.

Clinical Research Article

January 4, 2024
Pectoral nerve blocks for transvenous subpectoral pacemaker insertion in children: a randomized controlled study
Ahmed Mohamed Elhaddad, Salwa Mohamed Hefnawy, Mohamed Abd El-Aziz, Mahmoud Mostafa Ebraheem, Ahmed Kareem Mohamed
Korean J Anesthesiol. 2023;76(5):424-432.

Clinical Research Article

January 12, 2023
Pediatric perioperative fluid management
Hyungmook Lee, Jin Tae Kim
Korean J Anesthesiol. 2023;76(6):519-530.

Review Article

April 19, 2023
Quality of recovery in hospital and disability-free survival at three months after major abdominal surgery
Yuki Kinugasa, Mitsuru Ida, Shohei Nakatani, Kayo Uyama, Masahiko Kawaguchi
Korean J Anesthesiol. 2023;76(6):567-574.

Clinical Research Article

May 10, 2023
Serratus posterior superior intercostal plane block: novel block for minimal invasive cardiac surgery -A report of three cases-
Bora Bilal, Bahadir Ciftci, Selcuk Alver, Ali Ahiskalioglu, Serkan Tulgar
Korean J Anesthesiol. 2024;77(1):166-168.

Letter to the Editor

October 18, 2023
The incidences of nausea and vomiting after general anesthesia with remimazolam versus sevoflurane: a prospective randomized controlled trial[commentary-article]
Yeong Min Yoo, Jae Hong Park, Ki Hwa Lee, Ah Hyeon Yi, Tae Kyun Kim
Korean J Anesthesiol. 2024;77(4):441-449.

Clinical Research Article

April 19, 2024
Effects of remimazolam versus dexmedetomidine on recovery after transcatheter aortic valve replacement under monitored anesthesia care: a propensity score-matched, non-inferiority study[commentary-article][commentary-article]
Ji-Hyeon Kim, Jae-Sik Nam, Wan-Woo Seo, Kyung-Woon Joung, Ji-Hyun Chin, Wook-Jong Kim, Dae-Kee Choi, In-Cheol Choi
Korean J Anesthesiol. 2024;77(5):537-545.

Clinical Research Article

July 23, 2024
Ultrasound-guided trans-incisional quadratus lumborum block versus ultrasound-guided caudal analgesia in pediatric open renal surgery: a randomized trial
Amin M. Alansary, Atef Badawy, Marwa A. K. Elbeialy
Korean J Anesthesiol. 2023;76(5):471-480.

Clinical Research Article

January 26, 2023
Intravenous versus perineural dexmedetomidine as adjuvant in adductor canal block for total knee arthroplasty
Maha Ahmed Abo-Zeid Salim, Sherine Bakrey, Rania Elmohamady Elbadrawy
Korean J Anesthesiol. 2023;76(4):307-316.

Clinical Research Article

February 3, 2023
Comparison of different nonsteroidal anti-inflammatory drugs for cesarean section: a systematic review and network meta-analysis
Iona Murdoch, Anthony L Carver, Pervez Sultan, James E O’Carroll, Lindsay Blake, Brendan Carvalho, Desire N. Onwochei, Neel Desai
Korean J Anesthesiol. 2023;76(6):597-616.

Clinical Research Article

April 17, 2023
Does intravenous patient-controlled analgesia or continuous block prevent rebound pain following infraclavicular brachial plexus block after distal radius fracture fixation? A prospective randomized controlled trial
Jong-hyuk Lee, Ha-jung Kim, Jae Kwang Kim, Sungjoo Cheon, Young Ho Shin
Korean J Anesthesiol. 2023;76(6):559-566.

Clinical Research Article

April 24, 2023
Korean clinical practice guidelines for diagnostic and procedural sedation
Sang-Hyun Kim, Young-Jin Moon, Min Suk Chae, Yea-Ji Lee, Myong-Hwan Karm, Eun-Young Joo, Jeong-Jin Min, Bon-Nyeo Koo, Jeong-Hyun Choi, Jin-Young Hwang, et al.
Korean J Anesthesiol. 2024;77(1):5-30.

Review Article

November 16, 2023
Comparison of remimazolam and desflurane in emergence agitation after general anesthesia for nasal surgery: a prospective randomized controlled study
Sung-Ae Cho, So-min Ahn, Woojin Kwon, Tae-Yun Sung
Korean J Anesthesiol. 2024;77(4):432-440.

Clinical Research Article

May 7, 2024
  • Journal Impact Factor 4.2
  • SCImago Journal & Country Rank
  • Analgesic efficacy of the external oblique intercostal fascial plane block on postoperative acute pain in laparoscopic sleeve gastrectomy: a randomized controlled trial. Korean J Anesthesiol. 2025;78:159-170
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