Korean Journal of Anesthesiology

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Determination of the 95% effective dose of remimazolam to achieve loss of consciousness during anesthesia induction in different age groups: Juyeon Oh, Sung Yong Park, Sook Young Lee, Ju Yeol Song, Ga Yun Lee, et al.; Korean J Anesthesiol. 2022;75(6):510-517.

Review Article

October 17, 2022

Current evidence of ultrasound-guided fascial plane blocks for cardiac surgery: a narrative literature review

Boohwi Hong, Chahyun Oh, Yumin Jo, Soomin Lee, Seyeon Park, et al.

Korean J Anesthesiol. 2022;75(6):460-472.

Fascial plane blocks are useful for multimodal analgesia after cardiac surgery since they can provide effective analgesia without the serious risks associated with conventional techniques such as neuraxial hematoma and pneumothorax. This narrative review covers blocks performed at the parasternal intercostal, interpectoral, pectoserratus, serratus anterior, erector spinae, and retrolaminar planes, which are targets for fascial plane blocks in cardiac surgery. Brief anatomical considerations, mechanisms, and currently available evidence are reviewed. Additionally, recent evidence on fascial plane blocks for subcutaneous-implantable cardioverter-defibrillator implantation are also reviewed.

Review Article

July 5, 2022

Erector spinae plane block in children: a narrative review

Monica Lucente, Giulia Ragonesi, Marco Sanguigni, Fabio Sbaraglia, Alessandro Vergari, et al.

Korean J Anesthesiol. 2022;75(6):473-486.

The erector spinae plane block (ESPB) is a novel technique used in both adult and pediatric patients. Its use in children has mostly been described in terms of perioperative pain management for various types of surgery. After its introduction, anesthesiologists began using ESPBs in various surgical settings. As adequate analgesia along with a low complication rate were reported, interest in this technique dramatically increased. Many studies in adults and children, including randomized controlled trials, have been published, resulting in the emergence of different clinical indications, with various technical and pharmacological approaches currently evident in the literature. This narrative review aims to analyze the current evidence in order to guide...

Clinical Research Article

June 28, 2022

Effect of equipotent doses of propofol and sevoflurane on endoplasmic reticulum stress during breast cancer surgery

Chung-Sik Oh, Seung Wan Hong, Sarah Park, Yubi Kwon, Seong-Hyop Kim

Korean J Anesthesiol. 2022;75(6):487-495.

Background: Numerous studies suggest that intravenous propofol is superior to inhaled volatile anesthetic. This study compared the changes in the endoplasmic reticulum (ER) stress of cancer cells and lymphocytes after propofol- and sevoflurane-based anesthesia during breast cancer surgery. Methods: We randomized 53 patients undergoing breast cancer surgery to propofol (n = 28) and sevoflurane (n = 25) anesthesia groups. Blood samples were obtained immediately before inducing anesthesia, and 1 and 24 h postoperatively. Human breast cancer cell lines were cultured and treated with patient plasma, and the frequency of C/EBP...

Clinical Research Article

June 15, 2022

Accuracy of suprascapular notch cross-sectional area by MRI in the diagnosis of suprascapular nerve entrapment syndrome: a retrospective pilot study

Jiyeon Park, Min-Ying Su, Young Uk Kim

Korean J Anesthesiol. 2022;75(6):496-501.

Background: Previous studies have demonstrated that morphological changes in the suprascapular notch are closely associated with suprascapular nerve entrapment syndrome (SNES). Thus, we hypothesized that the suprascapular notch cross-sectional area (SSNCSA) could be a good diagnostic parameter to assess SNES. Methods: We acquired suprascapular notch data from 10 patients with SNES and 10 healthy individuals who had undergone shoulder magnetic resonance imaging (S-MRI) and had no evidence of SNES. T2-weighted coronal magnetic resonance images were acquired from the shoulder. We analyzed the SSNCSA at the shoulder on S-MRI using our image-analysis...

Clinical Research Article

May 18, 2022

Feasibility and efficacy of erector spinae plane block versus transversus abdominis plane block in laparoscopic bariatric surgery: a randomized comparative trial

Mohamed Elshazly, Yasser Mohamed EL-Halafawy, Dina Zakaria Mohamed, Khaled Abd El Wahab, Tamer Mohamed Kheir Mohamed

Korean J Anesthesiol. 2022;75(6):502-509.

Background: Overweight and obesity are growing public health concerns worldwide. Bariatric surgery is a modality of weight reduction; however, postoperative pain can increase the length of hospital stay, with all the associated consequences. While regional anesthesia is an available option, the feasibility of performing abdominal wall blocks on patients with obesity is questionable. Methods: Sixty adult patients with a body mass index of 40–50 kg/m2 undergoing laparoscopic bariatric surgery were randomly assigned to receive either an ultrasound-guided transversus abdominis plane (TAP) or erector spinae plane (ESP) block. The primary outcome was...

Clinical Research Article

August 1, 2022

Determination of the 95% effective dose of remimazolam to achieve loss of consciousness during anesthesia induction in different age groups

Juyeon Oh, Sung Yong Park, Sook Young Lee, Ju Yeol Song, Ga Yun Lee, et al.

Korean J Anesthesiol. 2022;75(6):510-517.

Background: Remimazolam is a new ultra short-acting benzodiazepine originally developed as an improved version of midazolam. Recent studies have demonstrated non-inferiority of remimazolam to propofol in general anesthesia. However, to date, few studies have investigated the induction bolus dose of remimazolam required to achieve general anesthesia. We aimed to determine the 95% effective dose (ED95) of remimazolam bolus required to achieve loss of consciousness (LOC) and the appropriate doses for different age groups. Methods: Patients aged 20–79 years with the American Society of Anesthesiologists physical status of I or II were...

Experimental Research Article

August 1, 2022

Dexmedetomidine attenuates subarachnoid hemorrhage-induced acute lung injury through regulating autophagy and TLR/NFκB signaling pathway

Dong Woo Han, Ju Eun Oh, Beom Jin Lim, Yeonseung Han, Young Song

Korean J Anesthesiol. 2022;75(6):518-529.

Background: Acute lung injury (ALI) is the most serious complication of subarachnoid hemorrhage (SAH). We investigated role of autophagy and inflammatory signaling pathways in lung damage and therapeutic effects of dexmedetomidine (DEX). Methods: Fifty male Wistar rats were randomly divided into five groups: sham, SAH, SAH+ DEX5, SAH+DEX25, and SAH+DEX50. SAH was induced using endovascular perforation technique. All rats received mechanical ventilation for 60 minutes. At 2 and 24 h of SAH induction, SAH+DEX groups were treated with 5, 25, and 50 µg/kg of DEX, respectively. Histological ALI score and pulmonary...

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Korean Journal of Anesthesiology1968 (v1 n1) to 2008 (v55 n6)

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Hydrolocation assisted subclavian venous catheterization -two case reports-. Korean J Anesthesiol. 2022;75:445-448

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