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Comparison of analgesic effects between programmed intermittent epidural boluses and continuous epidural infusion after cesarean section: a randomized controlled study
Yu Jeong Bang, Heejoon Jeong, RyungA Kang, Ji-Hee Sung, Suk-Joo Choi, et al.
Korean J Anesthesiol. 2024;77(3):374-383.

Review Article

January 17, 2024


Intraoperative pediatric electroencephalography monitoring: an updated review
Ian Yuan, Choon L. Bong, Jerry Y. Chao
Korean J Anesthesiol. 2024;77(3):289-305.

Intraoperative electroencephalography (EEG) monitoring under pediatric anesthesia has begun to attract increasing interest, driven by the availability of pediatric-specific EEG monitors and the realization that traditional dosing methods based on patient movement or changes in hemodynamic response often lead to imprecise dosing, especially in younger infants who may experience adverse events (e.g., hypotension) due to excess anesthesia. EEG directly measures the effects of anesthetics on the brain, which is the target end-organ responsible for inducing loss of consciousness. Over the past ten years, research on anesthesia and computational neuroscience has improved our understanding of intraoperative pediatric EEG monitoring and expanded the utility of EEG in clinical practice. ...

Review Article

January 29, 2024


Perioperative management of patients with cardiac implantable electronic devices
Minsu Kim, Chang Hee Kwon
Korean J Anesthesiol. 2024;77(3):306-315.

The use of cardiac implantable electronic devices (CIEDs) has increased significantly in recent years. Consequently, more patients with CIEDs will undergo surgery during their lifetime, and thus the involvement of anesthesiologists in the perioperative management of CIEDs is increasing. With ongoing advancements in technology, many types of CIEDs have been developed, including permanent pacemakers, leadless pacemakers, implantable cardioverter defibrillators, cardiac resynchronization therapy-pacemakers/defibrillators, and implantable loop recorders. The functioning of CIEDs exposed to an electromagnetic field can be affected by electromagnetic interference, potential sources of which can be found in the operating room. Thus, to prevent potential adverse events caused by electromagnetic interference in the operating room, anesthesiologists must have knowledge...

Statistical Round

April 29, 2024


Alternatives to the P value: connotations of significance
Junyong In, Dong Kyu Lee
Korean J Anesthesiol. 2024;77(3):316-325.

The statistical significance of a clinical trial analysis result is determined by a mathematical calculation and probability based on null hypothesis significance testing. However, statistical significance does not always align with meaningful clinical effects; thus, assigning clinical relevance to statistical significance is unreasonable. A statistical result incorporating a clinically meaningful difference is a better approach to present statistical significance. Thus, the minimal clinically important difference (MCID), which requires integrating minimum clinically relevant changes from the early stages of research design, has been introduced. As a follow-up to the previous statistical round article on P values, confidence intervals, and effect sizes, in this article, we present hands-on examples of MCID and...

Clinical Research Article

February 20, 2024


Comparison of preemptive and preventive intravenous acetaminophen on opioid consumption in pediatrics undergoing posterior spinal fusion surgery: a randomized controlled trial
Yeon Ju Kim, Ha-Jung Kim, Sehee Kim, Hyungtae Kim, Choon Sung Lee, et al.
Korean J Anesthesiol. 2024;77(3):326-334.

Background: Posterior spinal fusion (PSF), commonly used for adolescent idiopathic scoliosis (AIS), causes severe postoperative pain. Intravenous (IV) administration of acetaminophen has shown promise for opioid-sparing analgesia; however, its analgesic effect and optimal timing for its standard use remain unclear. Our study aimed to evaluate the analgesic effect and optimal timing of IV acetaminophen administration in pediatric and adolescent patients undergoing PSF and requiring adequate pain control. Methods: This prospective, randomized, triple-blind trial was conducted in patients aged 11–20 undergoing PSF. Participants were randomized into three groups: the preemptive group (received...

Clinical Research Article

February 5, 2024


Comparison of effects of telmisartan versus valsartan on post-induction hypotension during noncardiac surgery: a prospective observational study
Chung-Sik Oh, Jun Young Park, Seong-Hyop Kim
Korean J Anesthesiol. 2024;77(3):335-344.

Background: Telmisartan is considered more potent than valsartan. Hemodynamic response during anesthesia induction may be influenced by anti-hypertension (HTN) medication. The present study compared the effect of anti-HTN medications on post-induction hypotension during noncardiac surgeries. Methods: This observational study standardized the anesthetic regimen across patients, with hypotension defined as mean blood pressure (BP) of less than 65 mmHg. The hemodynamic changes within 5 min before and after endotracheal intubation, and within 10 min before and after surgical incision were measured. Transthoracic echocardiographic evaluation of the left ventricle (LV) during anesthesia induction...

Clinical Research Article

March 12, 2024


Efficacy of intraoperative blood salvage and autotransfusion in living-donor liver transplantation: a retrospective cohort study
Jongchan Lee, Sujung Park, Jae Geun Lee, Sungji Choo, Bon-Nyeo Koo
Korean J Anesthesiol. 2024;77(3):345-352.

Background: Liver transplantation (LT) may be associated with massive blood loss and the need for allogeneic blood transfusion. Intraoperative blood salvage autotransfusion (IBSA) can reduce the need for allogeneic blood transfusion. This study aimed to investigate the effectiveness of blood salvage in LT. Methods: Among 355 adult patients who underwent elective living-donor LT between January 1, 2019, and December 31, 2022, 59 recipients without advanced hepatocellular carcinoma received IBSA using Cell Saver (CS group). Based on sex, age, model for end-stage liver disease (MELD) score, preoperative laboratory results, and other factors, 118 of the 296 recipients who did not undergo IBSA were matched using propensity score (non-CS group). The primary outcome...

Clinical Research Article

March 5, 2024


Comparison of lung aeration loss in open abdominal oncologic surgeries after ventilation with electrical impedance tomography-guided PEEP versus conventional PEEP: a pilot feasibility study
A. R. Karthik, Nishkarsh Gupta, Rakesh Garg, Sachidanand Jee Bharati, M. D. Ray, et al.
Korean J Anesthesiol. 2024;77(3):353-363.

Background: Existing literature lacks high-quality evidence regarding the ideal intraoperative positive end-expiratory pressure (PEEP) to minimize postoperative pulmonary complications (PPCs). We hypothesized that applying individualized PEEP derived from electrical impedance tomography would reduce the severity of postoperative lung aeration loss, deterioration in oxygenation, and PPC incidence. Methods: A pilot feasibility study was conducted on 36 patients who underwent open abdominal oncologic surgery. The patients were randomized to receive individualized PEEP or conventional PEEP at 4 cmH2O. The primary outcome was the impact of individualized PEEP on changes in the modified lung...

Clinical Research Article

March 14, 2024


The minimum effective concentration (MEC90) of bupivacaine for an ultrasound-guided suprainguinal fascia iliaca compartment block for analgesia in knee surgery: a dose-finding study
Caner Genc, Serkan Tulgar, Murat Unal, Ahmet Serhat Genc, Lokman Kehribar, et al.
Korean J Anesthesiol. 2024;77(3):364-373.

Background: In recent years, the suprainguinal fascia iliaca compartment block (SFICB) has become more common in clinical practice. This assessor-blinded dose-finding study aimed to determine the minimum effective concentration (MEC90, MEC95) of bupivacaine for a single-injection SFICB in patients undergoing arthroscopic anterior cruciate ligament repair. Methods: This prospective study was conducted at a tertiary hospital (postoperative recovery room and ward). The SFICB was performed as a postsurgical intervention after spinal anesthesia. Seventy patients were allocated using the biased-coin design up-and-down sequential method. The ultrasound-guided...

Clinical Research Article

March 14, 2024


Comparison of analgesic effects between programmed intermittent epidural boluses and continuous epidural infusion after cesarean section: a randomized controlled study
Yu Jeong Bang, Heejoon Jeong, RyungA Kang, Ji-Hee Sung, Suk-Joo Choi, et al.
Korean J Anesthesiol. 2024;77(3):374-383.

Background: This study aimed to compare the analgesic effects of programmed intermittent epidural boluses (PIEB) and continuous epidural infusion (CEI) for postoperative analgesia after elective cesarean section (CS). Methods: Seventy-four women who underwent elective CS were randomized to receive either PIEB or CEI. The PIEB group received 4 ml-intermittent boluses of 0.11% ropivacaine every hour at a rate of 120 ml/h. The CEI group received a constant rate of 4 ml/h of 0.11% ropivacaine. The primary outcome was the pain score at rest at 36 h after CS. Secondary outcomes included...

Experimental Research Article

February 15, 2024


Neuroprotective effect of erythropoietin on anesthesia-induced neurotoxicity through the modulation of autophagy in Caenorhabditis elegans
Bon-Wook Koo, Hyun-Jung Shin, Sooyoung Jeon, Jung Hyun Bang, Sang-Hwan Do, et al.
Korean J Anesthesiol. 2024;77(3):384-391.

Background: The anti-oxidative, anti-inflammatory, and anti-apoptotic effects of erythropoietin may provide neuroprotective effects. Erythropoietin also modulates autophagy signaling that may play a role in anesthesia-induced neurotoxicity (AIN). Herein, we investigated whether AIN can be attenuated by the neuroprotective effect of erythropoietin in the Caenorhabditis elegans (C. elegans). Methods: Synchronized worms were divided into the control, Iso, EPO, and EPO-Iso groups. The chemotaxis index (CI) was evaluated when they reached the young adult stage. The lgg-1::GFP-positive puncta per seam cell were used to determine the autophagic events. The erythropoietin-mediated pathway of autophagy...
Risk factors for chloral hydrate sedation failure in pediatric patients: a retrospective analysis
Young-Eun Jang, Jung-Bin Park, Pyoyoon Kang, Sang-Hwan Ji, Eun-Hee Kim, Ji-Hyun Lee, Hee-Soo Kim, Jin-Tae Kim
[Epub ahead of print]

Clinical Research Article

July 2, 2024
Effect of lipid emulsion on vasoconstriction induced by epinephrine or norepinephrine in isolated rat aorta
Soo Hee Lee, Kyeong-Eon Park, Kibaek Eum, Yeran Hwang, Seong-Ho Ok, Gyujin Sim, Dumidu Perera, Henri K. Ravald, Youngho Park, Susanne K. Wiedmer, et al.
[Epub ahead of print]

Experimental Research Article

June 25, 2024
Venous air emboli during esophagoscopy confirmed by computed tomographic pulmonary angiography -a case report-
Thadakorn Tantisarasart, Thara Tantichamnankul, Chanatthee Kitsiripant, Panjai Choochuen
[Epub ahead of print]
Corrects: Korean J Anesthesiol 2024 4; 77(2): 278

Corrigendum

June 25, 2024
Utilization of the pericapsular nerve group block in preoperative rehabilitation of patients with femoral neck fractures: a case series
Zhuan Jin, Daisuke Sugiyama, Fumiya Higo, Takahiro Hirata, Osamu Kobayashi, Hiroshi Morimatsu, Kenichi Ueda
[Epub ahead of print]

Case Report

June 19, 2024
The effects of sugammadex on isolated human internal mammary artery and saphenous vein rings
Mert C. Ongun, Bahar Oc, Mehmet Oc, Hulagu Bariskaner
[Epub ahead of print]

Letter to the Editor

May 22, 2024
Response to letter
Byungjin Choi, Ah Ran Oh, Jungchan Park, Seunghwa Lee
[Epub ahead of print]

Letter to the Editor

May 20, 2024
Effect of perioperative intravenous ibuprofen versus acetaminophen on postoperative opioid consumption and pain after general anesthesia: a systematic review and meta-analysis with trial sequential analysis of randomized controlled trials
Sung Hye Kim, Hyun Kang, In-Jung Jun, Hye Won Park, Byung Hoon Yoo, Yun-Hee Lim, Kye-Min Kim
[Epub ahead of print]

Clinical Research Article

May 7, 2024
Comparison of remimazolam and desflurane in emergence agitation after general anesthesia for nasal surgery: a prospective randomized controlled study
Sung-Ae Cho, So-min Ahn, Woojin Kwon, Tae-Yun Sung
[Epub ahead of print]

Clinical Research Article

May 7, 2024
Renal implications of pneumoperitoneum in laparoscopic surgery: mechanisms, risk factors, and preventive strategies
Gianluca Villa, Marco Fiorentino, Eleonora Cappellini, Sergio Lassola, Silvia De Rosa
[Epub ahead of print]

Review Article

April 26, 2024
Response to "Comment on Comparison of the pericapsular nerve group block with the intra-articular and quadratus lumborum blocks in primary total hip arthroplasty: a randomized controlled trial"
Tayfun Et, Muhammet Korkusuz
[Epub ahead of print]

Letter to the Editor

April 25, 2024
Assessment of fluid infusion rate using a pulse oximeter: a pilot study
Yeiheum Park, Sungho Moon
[Epub ahead of print]

Letter to the Editor

April 24, 2024
Ultrasound mapping of soft tissue vascular anatomy proximal to the larynx: a prospective cohort study
Alessandro De Cassai, Margherita Iuzzolino, Silvia De Pinto, Giovanni Zecchino, Tommaso Pettenuzzo, Annalisa Boscolo, Eugenio Biamonte, Paolo Navalesi, Marina Munari
[Epub ahead of print]

Clinical Research Article

April 23, 2024
The incidences of nausea and vomiting after general anesthesia with remimazolam versus sevoflurane: a prospective randomized controlled trial
Yeong Min Yoo, Jae Hong Park, Ki Hwa Lee, Ah Hyeon Yi, Tae Kyun Kim
[Epub ahead of print]

Clinical Research Article

April 19, 2024
Retro superior costotransverse ligament space block as an effective analgesia after laparoscopic gastrectomy -a case report-
Youngin Lee, Seunguk Bang, Jihyun Chung, Jookyoung Moon
[Epub ahead of print]

Case Report

April 15, 2024
Postoperative neurocognitive disorders in ambulatory surgery: a narrative review
Junyong In, Brian Chen, Hansu Bae, Sakura Kinjo
[Epub ahead of print]

Review Article

April 3, 2024
Damage-associated molecular patterns as a mechanism of sevoflurane-induced neuroinflammation in neonatal rodents
Young-Eun Joe, Ji Hae Jun, Ju Eun Oh, Jeong-Rim Lee
[Epub ahead of print]

Experimental Research Article

April 1, 2024
Tranexamic acid - a promising hemostatic agent with limitations: a narrative review
Dong Joon Kim, Su Yeon Cho, Ki Tae Jung
[Epub ahead of print]

Review Article

August 21, 2023
Robot-assisted radical prostatectomy: comparison of subarachnoid analgesia, erector spine plane block, and intravenous analgesia for postoperative pain management
Pasquale Buonanno, Nicola Logrieco, Annachiara Marra, Lorenzo Spirito, Gianluigi Califano, Federica Blasio, Nausica Di Falco, Achille Aveta, Gianluca Spena, Giuseppe Servillo
[Epub ahead of print]

Clinical Research Article

June 14, 2023
WITHDRAWN:Smartphones are definitely a boon in operation theatre if used smartly enough
Anju Gupta, Nishkarsh Gupta
[Epub ahead of print]

Letter to the Editor

June 20, 2019
  • Journal Impact Factor 4.2
  • SCImago Journal & Country Rank
  • Sudden ventricular fibrillation due to absence of pericardium in left upper lobectomy -a case report-. Korean J Anesthesiol. 2024;77:401-404
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