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Effect of chemotherapy on effect-site concentration of propofol for loss of consciousness in patients with colorectal cancer
Seunghee Ki, Yongwon Cho, Youngkyung Choi, Sehun Lim, Myounghun Kim, et al.
Korean J Anesthesiol. 2022;75(2):160-167.

Review Article

February 17, 2022


Different perspectives for monitoring nociception during general anesthesia
Pablo Martinez-Vazquez, Erik Weber Jensen
Korean J Anesthesiol. 2022;75(2):112-123.

Safe anesthesia is achieved using objective methods that estimate the patient’s state during different phases of surgery. A patient’s state under anesthesia is characterized by three major aspects, which are linked to the main effects produced by each of the families of anesthetic agents administered: hypnosis, analgesia, and muscular relaxation. While quantification techniques designed to assess muscular relaxation under neuromuscular blocking agents have a relatively long history with a high degree of standardization and understanding (e.g., the train-of-four), the knowledge and techniques used to the depth of hypnosis assessment suffer from a lesser degree in both standardization and interpretation due to brain complexity. The problem of standardization and interpretation in...

Review Article

February 8, 2022


How general anesthetics work: from the perspective of reorganized connections within the brain
Teo Jeon Shin, Pil-Jong Kim, Bernard Choi
Korean J Anesthesiol. 2022;75(2):124-138.

General anesthesia is critical for various procedures and surgeries. Despite the widespread use of anesthetics, their precise mechanisms remain poorly understood. Anesthetics inevitably act on the brain, primarily through the modulation of target receptors. Even if the action is specific to an individual neuron, however, long-range effects can occur due to the tremendous interconnectedness of neuronal activity. The strength of this connectivity can be understood using mathematical models that allow for the study of neuronal connectivity dynamics. These models also allow researchers to develop hypotheses on the candidate mechanisms of action of different types of anesthesia. This review highlights the theoretical background associated with the study of the mechanisms of...

Statistical Round

March 3, 2022


The principles of presenting statistical results using figures
Jae Hong Park, Dong Kyu Lee, Hyun Kang, Jong Hae Kim, Francis Sahngun Nahm, et al.
Korean J Anesthesiol. 2022;75(2):139-150.

Tables and figures are commonly adopted methods for presenting specific data or statistical analysis results. Figures can be used to display characteristics and distributions of data, allowing for intuitive understanding through visualization and thus making it easier to interpret the statistical results. To maximize the positive aspects of figure presentation and increase the accuracy of the content, in this article, the authors will describe how to choose an appropriate figure type and the necessary components to include. Additionally, this article includes examples of figures that are commonly used in research and their essential components using virtual data.

Clinical Research Article

October 20, 2021


Noninvasive cardiac output measurements are inaccurate in patients with severe aortic valve stenosis undergoing transcatheter aortic valve implantation
Musashi Yahagi, Kyuma Omi, Takuma Maeda
Korean J Anesthesiol. 2022;75(2):151-159.

Background: Noninvasive cardiac output (CO) measured using ClearSight™ eliminates the need for intra-arterial catheter insertion. The purpose of this study was to examine the accuracy of non-invasive CO measurement in patients with severe aortic valve stenosis (AS). Methods: Twenty-eight patients undergoing elective transcatheter aortic valve implantation were prospectively enrolled in this study. The CO was simultaneously measured twice before and twice after valve deployment (total of four times) per patient, and the CO was compared between the ClearSight (COClearSight) system and the pulmonary artery catheter (PAC)...

Clinical Research Article

September 17, 2021


Effect of chemotherapy on effect-site concentration of propofol for loss of consciousness in patients with colorectal cancer
Seunghee Ki, Yongwon Cho, Youngkyung Choi, Sehun Lim, Myounghun Kim, et al.
Korean J Anesthesiol. 2022;75(2):160-167.

Background: The depth of anesthesia is an essential factor in surgical prognosis. The neurotoxic effect of chemotherapeutic drugs affects the sensitivity to anesthetics. This study was conducted to determine whether the effect-site concentration (Ce) of propofol for loss of consciousness (LOC) differs in patients undergoing preoperative chemotherapy. Methods: A total of 60 patients scheduled for surgery for colorectal cancer under general anesthesia were included in this study. Patients who had received chemotherapy comprised the experimental (C) group, and those without a previous history of chemotherapy comprised the control (N) group....

Clinical Research Article

December 16, 2021


Delphi consensus on the American Society of Anesthesiologists’ physical status classification in an Asian tertiary women’s hospital
Tarig Osman, Eileen Lew, Ban L. Sng, Rajive Dabas, Konstadina Griva, et al.
Korean J Anesthesiol. 2022;75(2):168-177.

Background: The American Society of Anesthesiologists (ASA) score is generated based on patients’ clinical status. Accurate ASA classification is essential for the communication of perioperative risks and resource planning. Literature suggests that ASA classification can be automated for consistency and time-efficiency. To develop a rule-based algorithm for automated ASA classification, this study seeks to establish consensus in ASA classification for clinical conditions encountered at a tertiary women’s hospital. Methods: Thirty-seven anesthesia providers rated their agreement on a 4-point Likert scale to ASA scores assigned to items via the Delphi technique. After...

Clinical Research Article

November 4, 2021


Subanesthetic intravenous ketamine vs. caudal bupivacaine for postoperative analgesia in children undergoing infra-umbilical surgeries: a non-inferiority randomized, single-blind controlled trial
Alok Kumar Sahoo, Satyajeet Misra, Bikram Kishore Behera, Anand Srinivasan, Sritam Swarup Jena, et al.
Korean J Anesthesiol. 2022;75(2):178-184.

Background: Subanesthetic intravenous (IV) ketamine acts as an analgesic and has opioid-sparing effects, particularly for acute postoperative pain; however, its effectiveness in children is understudied. The primary aim of this study was to evaluate the non-inferiority of subanesthetic IV ketamine vs. caudal bupivacaine for postoperative analgesia in children undergoing infraumbilical surgery. Methods: Children aged < 6 years were enrolled in this single-blind study and randomized to receive either subanesthetic IV ketamine (0.3 mg/kg) or caudal 0.125% bupivacaine (1 ml/kg) along with general anesthesia. Postoperative pain was assessed using...
Remimazolam – current knowledge on a new benzodiazepine intravenous anesthetic agent
Seong-Hyop Kim, Jörg Fechner
[Epub ahead of print]

Review Article

May 19, 2022
Another new kid on the BLOCK for pain control in pediatric cardiac surgery
Woosuk Chung
[Epub ahead of print]

Editorial

May 19, 2022
Video Laryngoscope versus USB borescope aided endotracheal intubation in adults with anticipated difficult airway: a prospective randomized controlled study
Mohamed Elshazly, Mark Medhat, Sahar Marzouk, Enas Mohamed Samir
[Epub ahead of print]

Clinical Research Article

May 18, 2022
The Feasibility and Efficacy of erector spinae plane block versus Transversus Abdominis Plane Block In Laparoscopic Bariatric Surgery : A Randomized Comparative Trial
Mohamed Elshazly, Yasser Mohamed EL-Halafawy, Dina Zakaria Mohamed, Khaled Abd El Wahab, Tamer Mohamed Kheir Mohamed
[Epub ahead of print]

Clinical Research Article

May 18, 2022
On the road to make KJA’s review process robust, transparent, and credible: retracted study in systematic review
Geun Joo Choi, Hyun Kang
[Epub ahead of print]

Editorial

May 11, 2022
Psychogenic coma after general anesthesia with remimazolam and remifentanil – a case report
Song Hyun Kim, Kye Min Kim, Yun-Hee Lim, Byung Hoon Yoo, Joonho Cho, In-Jung Jun
[Epub ahead of print]

Case Report

May 10, 2022
Association of HLA-DPA1 gene polymorphism with prolonged mechanical ventilation in patients undergoing liver transplantation
Eun Jung Kim, Min-soo Kim, Myoung Soo Kim, Junhyun Nam, Seung Ho Choi
[Epub ahead of print]

Clinical Research Article

May 3, 2022
Cadaveric investigation about the spread of thoracoabdominal nerve block through a perichondral approach and modified approach
Bahadir Ciftci, Haci Ahmet Alici, Gamze Ansen, Bayram Ufuk Sakul, Serkan Tulgar
[Epub ahead of print]

Letter to the Editor

April 26, 2022
Anatomical classification and clinical application of thoracic paraspinal blocks
Shin Hyung Kim
[Epub ahead of print]

Review Article

April 4, 2022
Therapeutic hypothermia for acute myocardial infarction: a narrative review of evidence from animal and clinical studies
Ki Tae Jung, Aneesh Bapat, Young-Kug Kim, William J. Hucker, Kichang Lee
[Epub ahead of print]

Review Article

March 30, 2022
Artificial intelligence in perioperative medicine: a narrative review
Hyun-Kyu Yoon, Hyun-Lim Yang, Chul-Woo Jung, Hyung-Chul Lee
[Epub ahead of print]

Review Article

March 29, 2022
Postoperative opioid consumption data repository incorporated in electric medical record based on PCA device data extraction program
Chahyun Oh, Boohwi Hong, Gwanhoon Kim, Seok-Hwa Yoon, Yong-Sup Shin
[Epub ahead of print]

Letter to the Editor

March 23, 2022
Propofol abuse among healthcare workers: an analysis of criminal cases using the database of the Supreme Court of South Korea’s judgments
Hye-Yeon Cho, Yoonbin Hwang, SuHwan Shin, Susie Yoon, Ho-Jin Lee
[Epub ahead of print]

Clinical Research

March 15, 2022
Fatal multiorgan dysfunction following repeated iodinated radiocontrast injection in a patient receiving low-dose oral methotrexate
Balaji Vaithialingam, Radhakrishnan Muthuchellappan, Mouleeswaran Sundaram
[Epub ahead of print]

Case Report

March 14, 2022
Comparison between the coronal diameters of the cervical spinal canal and spinal cord measured using computed tomography and magnetic resonance imaging in Korean patients
So Young Lee, In Young Kim, Kyung Wook Jeong, Taeha Ryu, Sang Kyu Kwak, Jin Yong Jung
[Epub ahead of print]

Clinical Research

March 11, 2022
Obstructive fibrinous pseudomembrane tracheitis after double lumen tube intubation: a case report
Jia-Hui Chua, Brenda L H Sim, Tina Koh Puay Theng, Sophia Chew
[Epub ahead of print]

Case Report

February 22, 2022
Perioperative analgesia research in pediatric open-heart surgery: the devil is in the details
Rohan Magoon, Brajesh Kaushal, Jes Jose
[Epub ahead of print]

Letter to the Editor

February 8, 2022
Combined cerebral and somatic near-infrared spectroscopy oximetry monitoring during liver surgery: an observational and non-interventional study
Yves Collin, Tina Hu, André Denault, Annik Fortier, William Beaubien-Souligny, Réal Lapointe, Franck Vandenbroucke-Menu
[Epub ahead of print]

Clinical Research Article

January 20, 2022
The effect of ultrasound-guided bilateral thoracic retrolaminar block on analgesia after pediatric open cardiac surgery: a randomized controlled double-blind study
Ibrahim Abdelbaser, Nabil A. Mageed, Sherif I. Elfayoumy, Mohamed Magdy, Mohamed M. Elmorsy, Mahmoud M. ALseoudy
[Epub ahead of print]

Clinical Research Article

January 12, 2022
Preoperative dexmedetomidine and intraoperative bradycardia in laparoscopic cholecystectomy: a meta-analysis with trial sequential analysis
Alessandro De Cassai, Nicolò Sella, Federico Geraldini, Francesco Zarantonello, Tommaso Pettenuzzo, Laura Pasin, Margherita Iuzzolino, Nicolò Rossini, Elisa Pesenti, Giovanni Zecchino, et al.
[Epub ahead of print]

Clinical Research Article

January 12, 2022
Efficacy of perineural versus intravenous dexamethasone in prolonging the duration of analgesia when administered with peripheral nerve blocks: a systematic review and meta-analysis
Elizabeth Sein Jieh Tan, Yan Ru Tan, Christopher Wei Yang Liu
[Epub ahead of print]

Clinical Research Article

December 29, 2021
Standard digit-based versus 90° rotation technique for supraglottic airway device insertion: a meta-analysis of randomized controlled trials
Chang-Hoon Koo, Ah-Young Oh, Young-Tae Jeon, Jung-Won Hwang, Jung-Hee Ryu
[Epub ahead of print]

Clinical Research Article

December 9, 2021
Reading beyond quantitative electroencephalography-based indices: A case of erroneously high Entropy values during ophthalmic surgery
Yuh-Shyan Wu, Po-Nien Chen, Gwo-Ching Sun, Kuang-I Cheng, Zhi-Fu Wu
[Epub ahead of print]

Letter to the Editor

November 22, 2021
Comparison of clinical performance of I-GelTM, LMA SupremeTM And Ambu AuraGainTM in adult patients during general anesthesia; a prospective and randomised study
Tejashri Chinthavali Lakshmi, Tanmay Tiwari, Jyotsna Agrawal, Rajni Kapoor, Vikrannth Vasanthakumar
[Epub ahead of print]

Clinical Research Article

October 20, 2021
Regional analgesia techniques for video-assisted thoracic surgery: a frequentist network meta-analysis
Yumin Jo, Seyeon Park, Chahyun Oh, Yujin Pak, Kuhee Jeong, Sangwon Yun, Chan Noh, Woosuk Chung, Yoon-Hee Kim, Young Kwon Ko, et al.
[Epub ahead of print]

Clinical Research Article

October 13, 2021
The novel use of biplane imaging for ultrasound-guided regional anesthesia
Nadia Hernandez, Sudipta Sen, Johanna Blair de Haan, Stephen Haskins, Amit Pawa
[Epub ahead of print]

Letter to the Editor

July 15, 2021
Novel use of ultrasound guidance in wide awake local anesthesia technique for clavicle surgery
Khalid Azizi, Sabah Benhamza, Youssef Motiaa
[Epub ahead of print]

Letter to the Editor

June 30, 2021
Smartphones are definitely a boon in operation theatre if used smartly enough
Anju Gupta, Nishkarsh Gupta
[Epub ahead of print]

Letter to the Editor

June 20, 2019
Comparison of priming versus slow injection for reducing etomidate-induced myoclonus: a randomized controlled study
Parul Mullick, Vandana Talwar, Shipra Aggarwal, Smita Prakash, Mridula Pawar
[Epub ahead of print]

Clinical Research Article

May 30, 2018
  • Novel use of ultrasound guidance in wide-awake local anesthesia technique for clavicle surgery. Korean J Anesthesiol. 2022;75:103-105
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