Korean Journal of Anesthesiology

Effects of remimazolam versus dexmedetomidine on recovery after transcatheter aortic valve replacement under monitored anesthesia care: a propensity score-matched, non-inferiority study: Ji-Hyeon Kim, Jae-Sik Nam, Wan-Woo Seo, Kyung-Woon Joung, Ji-Hyun Chin, et al.; Korean J Anesthesiol. 2024;77(5):537-545.

Review Article

April 3, 2024

Postoperative neurocognitive disorders in ambulatory surgery: a narrative review

Junyong In, Brian Chen, Hansu Bae, Sakura Kinjo

Korean J Anesthesiol. 2024;77(5):493-502.

Postoperative neurocognitive disorders (PoNCDs), such as postoperative delirium and cognitive dysfunction or decline can occur after surgery, especially in older patients. This significantly affects patient morbidity and surgical outcomes. Among various risk factors, recent studies have shown that preoperative frailty is associated with developing these conditions. Although the mechanisms underlying PoNCDs remain unclear, neuroinflammation appears to play an important role in their development. For the prevention and treatment of PoNCDs, medication modification, a balanced diet, and prehabilitation and rehabilitation programs have been suggested. The risk of developing PoNCDs is thought to be lower in ambulatory patients. However, owing to technological advancements, an increasing number of older and sicker patients are...

Statistical Round

August 30, 2024

Comprehensive guidelines for appropriate statistical analysis methods in research

Jonghae Kim, Dong Hyuck Kim, Sang Gyu Kwak

Korean J Anesthesiol. 2024;77(5):503-517.

Background: The selection of statistical analysis methods in research is a critical and nuanced task that requires a scientific and rational approach. Aligning the chosen method with the specifics of the research design and hypothesis is paramount, as it can significantly impact the reliability and quality of the research outcomes. Methods: This study explores a comprehensive guideline for systematically choosing appropriate statistical analysis methods, with a particular focus on the statistical hypothesis testing stage and categorization of variables. By providing a detailed examination of these aspects, this study aims to provide researchers with a solid foundation for informed methodological decision making. Moving beyond theoretical considerations, this study delves into the...

Clinical Research Article

August 19, 2024

Ramped versus sniffing position for Ambu^® AuraGain^TM insertion in patients with obesity: a randomized controlled study

Hye-won Jeong, Hong-Beom Bae, Leyeoin Lee, Woojeong Lee, Joungmin Kim

Korean J Anesthesiol. 2024;77(5):518-525.

Background: The ramped position facilitates mask ventilation and endotracheal intubation in patients with obesity. This study aimed to determine whether the ramped position improves supraglottic airway (SGA) insertion in patients with obesity. Methods: In this prospective, randomized, single-center trial, 48 obese patients undergoing elective surgery were randomized into either ramped or sniffing position groups. The Ambu® AuraGainTM (Ambu A/S), a second-generation SGA, was used. The primary outcome was the time required for the AuraGain insertion. Secondary outcomes included ease and number of insertion attempts, oropharyngeal leak pressure (OLP), and complications. The...

Clinical Research Article

July 2, 2024

Risk factors for chloral hydrate sedation failure in pediatric patients: a retrospective analysis

Young-Eun Jang, Jung-Bin Park, Pyoyoon Kang, Sang-Hwan Ji, Eun-Hee Kim, et al.

Korean J Anesthesiol. 2024;77(5):526-536.

Background: This study aimed to investigate the risk factors for chloral hydrate sedation failure and complications in a tertiary children’s hospital in South Korea. Methods: A retrospective analysis of pediatric procedural sedation with chloral hydrate between January 1, 2021, and March 30, 2022, was performed. The collected data included patient characteristics, sedation history, and procedure. Multivariable regression analysis was performed to identify the risk factors for procedural sedation failure and complications. Results: A total of 6,691 procedural sedation were included in the analysis; sedation failure following chloral hydrate (50 mg/kg) occurred in 1,457 patients (21.8%) and was associated with a higher rate of overall complications compared to those with successful sedation (17.5%...

Clinical Research Article

July 23, 2024

Effects of remimazolam versus dexmedetomidine on recovery after transcatheter aortic valve replacement under monitored anesthesia care: a propensity score-matched, non-inferiority study

Ji-Hyeon Kim, Jae-Sik Nam, Wan-Woo Seo, Kyung-Woon Joung, Ji-Hyun Chin, et al.

Korean J Anesthesiol. 2024;77(5):537-545.

Background: Minimalist transcatheter aortic valve replacement (TAVR) under monitored anesthesia care (MAC) emphasizes early recovery. Remimazolam is a novel benzodiazepine with a short recovery time. This study hypothesized that remimazolam is non-inferior to dexmedetomidine in terms of recovery after TAVR. Methods: In this retrospective observational study, remimazolam was compared to dexmedetomidine in patients who underwent TAVR under MAC at a tertiary academic hospital between July 2020 and July 2022. The primary outcome was timely recovery after TAVR, defined as discharge from the intensive care unit within the first day following the...

Clinical Research Article

August 6, 2024

The effect of non-steroidal anti-inflammatory drugs on postoperative delirium: a meta-analysis

Su Yeon Kim, Hyo-Seok Na, Jung-Hee Ryu, Hyun-Jung Shin

Korean J Anesthesiol. 2024;77(5):546-554.

Background: Neuroinflammation is postulated as a potential mechanism underlying postoperative delirium. This study aimed to investigate the impact of non-steroidal anti-inflammatory drug (NSAID) use on postoperative delirium. Methods: We conducted a literature search in electronic databases, including PubMed, EMBASE, CENTRAL, and Web of Science, to identify eligible randomized controlled studies. The primary outcome was the incidence of postoperative delirium, and the secondary outcomes included pain scores and the amounts of opioid used at 24 h postoperatively. We estimated the effect size through calculating the odds ratios (ORs) or mean differences (MDs) with 95% CIs, as appropriate. Results: In the analysis of eight studies involving 1,238 participants, the incidence of postoperative delirium was...

Experimental Research Article

June 25, 2024

Effect of lipid emulsion on vasoconstriction induced by epinephrine or norepinephrine in isolated rat aorta

Soo Hee Lee, Kyeong-Eon Park, Kibaek Eum, Yeran Hwang, Seong-Ho Ok, et al.

Korean J Anesthesiol. 2024;77(5):555-564.

Background: Epinephrine (EPI) or norepinephrine (NOR) is widely used to treat cardiovascular collapse during lipid emulsion (LE) resuscitation for drug toxicity. However, the effect of LE on the vasoconstriction caused by EPI or NOR remains unknown. The purpose of this study was to examine the effect of an LE (Intralipid) on the vasoconstriction caused by EPI and NOR in isolated rat aorta. Methods: The effect of LE on the vasoconstriction caused by EPI or NOR in isolated rat aorta was examined. Additionally, the effect of LE on the calcium increase caused by EPI or NOR was investigated. The distribution constant (KD: lipid to aqueous phase) of EPI or NOR between...

Pediatric sedation and monitored anesthesia care: from chloral hydrate to remimazolam Won-Jung Shin Korean J Anesthesiol. 2024;77(5):491-492. Editorial September 23, 2024 Full text PubReader ePub PDF	Postoperative neurocognitive disorders in ambulatory surgery: a narrative review Junyong In, Brian Chen, Hansu Bae, Sakura Kinjo Korean J Anesthesiol. 2024;77(5):493-502. Review Article April 3, 2024 Full text PubReader PDF PDF(Korean)
Comprehensive guidelines for appropriate statistical analysis methods in research Jonghae Kim, Dong Hyuck Kim, Sang Gyu Kwak Korean J Anesthesiol. 2024;77(5):503-517. Statistical Round August 30, 2024 Full text PubReader ePub PDF PDF(Korean)	Ramped versus sniffing position for Ambu^® AuraGain^TM insertion in patients with obesity: a randomized controlled study Hye-won Jeong, Hong-Beom Bae, Leyeoin Lee, Woojeong Lee, Joungmin Kim Korean J Anesthesiol. 2024;77(5):518-525. Clinical Research Article August 19, 2024 Full text PubReader ePub PDF PDF(Korean)
Risk factors for chloral hydrate sedation failure in pediatric patients: a retrospective analysis Young-Eun Jang, Jung-Bin Park, Pyoyoon Kang, Sang-Hwan Ji, Eun-Hee Kim, Ji-Hyun Lee, Hee-Soo Kim, Jin-Tae Kim Korean J Anesthesiol. 2024;77(5):526-536. Clinical Research Article July 2, 2024 Cited By 1 Full text PubReader ePub PDF PDF(Korean)	Effects of remimazolam versus dexmedetomidine on recovery after transcatheter aortic valve replacement under monitored anesthesia care: a propensity score-matched, non-inferiority study Ji-Hyeon Kim, Jae-Sik Nam, Wan-Woo Seo, Kyung-Woon Joung, Ji-Hyun Chin, Wook-Jong Kim, Dae-Kee Choi, In-Cheol Choi Korean J Anesthesiol. 2024;77(5):537-545. Clinical Research Article July 23, 2024 Cited By 1 Full text PubReader PDF PDF(Korean) Supplementary Material
The effect of non-steroidal anti-inflammatory drugs on postoperative delirium: a meta-analysis Su Yeon Kim, Hyo-Seok Na, Jung-Hee Ryu, Hyun-Jung Shin Korean J Anesthesiol. 2024;77(5):546-554. Clinical Research Article August 6, 2024 Full text PubReader ePub PDF PDF(Korean) Supplementary Material	Effect of lipid emulsion on vasoconstriction induced by epinephrine or norepinephrine in isolated rat aorta Soo Hee Lee, Kyeong-Eon Park, Kibaek Eum, Yeran Hwang, Seong-Ho Ok, Gyujin Sim, Dumidu Perera, Henri K.M. Ravald, Youngho Park, Susanne K. Wiedmer, et al. Korean J Anesthesiol. 2024;77(5):555-564. Experimental Research Article June 25, 2024 Full text PubReader ePub PDF PDF(Korean)
Utilization of the pericapsular nerve group block in preoperative rehabilitation of patients with femoral neck fractures -a case series- Zhuan Jin, Daisuke Sugiyama, Fumiya Higo, Takahiro Hirata, Osamu Kobayashi, Hiroshi Morimatsu, Kenichi Ueda Korean J Anesthesiol. 2024;77(5):565-569. Case Report June 19, 2024 Full text PubReader ePub PDF	A new treatment option for chronic refractory coccygodynia: ultrasound-guided sacral erector spinae plane block Tuba Tanyel Saraçoğlu, Burak Erken, Ergün Mendeş Korean J Anesthesiol. 2024;77(5):570-571. Letter to the Editor July 18, 2024 Full text PubReader ePub PDF
Comment on “Retro superior costotransverse ligament space block as an effective analgesia after laparoscopic gastrectomy” Raghuraman M Sethuraman Korean J Anesthesiol. 2024;77(5):571-572. Letter to the Editor July 12, 2024 Full text PubReader ePub PDF