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Korean Journal of Anesthesiology 1992;25(6):1195-1199.
DOI: https://doi.org/10.4097/kjae.1992.25.6.1195   
The Preventive Effect of Propofol on Postoperative Nausea and Vomiting after Strabismus Surgery in Pediatric Patients.
Hae Kyung Lee, Won Oak Kim, Hae Keum Kil, Jong Rae Kim
Department of Anesthesiology, Yonsei University College of Medicine, Seoul, Korea.
Nausea and vomiting are common problems after strabismus surgery in pediatric patients. We compared the effect of propofol with N2O with the effect of a conventional regimen consisting of halothane - N2O on the occurrence of oculocardiac reflex(OCR), recovery characteristics and the incidence of postoperative emesis after strabismus surgery in 46 ASA physical status I children. After intravenous injection of atropine(0.02 mg/kg), patients were randomly assigned to one of two groups. Group l(conrol) received thiopental, vecuronium, halothane and N2O; Group 2(study), propofol 2 mg/kg and vecuronium bolus followed by infusion of propofol 160 mg/kg/min. Patients in group 2 had more episodes of OCR response than group 1, but had shorter time to recovery from anesthesia(p<0;05). But there was no significant difference in the incidence of postoperative nausea and vomiting between two groups. We conclude that the sufficient doses of propofol only regimen and atropine preadministration(0.02 mg/kg) will be necessary in the strabismus surgery of children for the purposes of the prevention of intraoperative OCR, rapid recovery from anesthesia and reduction of postoperative emesis.
Key Words: Nausea; Vomiting; Oculocardiac reflex; Propofol


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