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Korean Journal of Anesthesiology 1990;23(6):879-883.
DOI: https://doi.org/10.4097/kjae.1990.23.6.879   
A Study on the Effect of Waste Anestheic Gases on the Sister Chromatid Exchanges of Peripheral Lymphocytes in Operating Room Personnel.
Young Seok Choi, Hak Sik Kim, Keon Kang
Department of Anesthesiology, Hae Sung General Hospital, Ulsan, Korea.
The authors examined the induntivity of sister chromatid exchanges (SCE) in peripheral lum-phocytes on the personnel working in the operating room and analyzed the factors associated with it to obtain data for their monitoring health status. The results obtained were as follows; 1) Average inductivity of SCE in peripheral lymphocytes of operating room perssonnel exposed to anesthetic gases was 7.85 per cell; it was significantly higher than in those who were not exposed (p< 0.05). 2) The inductivity of SCE in peripheral lymphocytes by age group and exposure duration was not statically significant (p<0.05). 3) The inductivity of SCE in the subjects with a smoking habit was significantly higher than those without a smoking habit (p<0.05). 4) There was no significant difference in the inductivity of SCE between the subjects with a drinking habit and those without it (p>0.05). 5) It is possible that the high inductivity of SCE in operating room personnel who both with drink and smoke was due to more the influence of their smoking than their drinking.
Key Words: Sister chromatid exchange; Anesthetic gases; Smoking


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