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Korean J Anesthesiol > Volume 55(5); 2008 > Article
Korean Journal of Anesthesiology 2008;55(5):543-548.
DOI: https://doi.org/10.4097/kjae.2008.55.5.543   
The comparison of intravenous anesthesia with fentanyl versus alfentanill during oocyte retrieval for in vitro fertilization.
Yong In Kang, Eun Chi Bang, Hyun Sook Lee, Kyung Sook Cho, Su Yeon Kim, Jung Ho Sul, Jun Young Kim, Tae Gi Yoon, Hyun Ha Seok
1Department of Anesthesiology and Pain Medicine, College of Medicine, Pochon CHA University, Seoul, Korea. anein09@naver.com
2Department of Obstetric and Gynecology, College of Medicine, Pochon CHA University, Seoul, Korea.
This study was carried out to compare the effect of intravenous anesthesia with fentanyl or alfentanil on the hemodynamic profile, sedation, recovery and side effect in the patients undergoing oocyte retrieval.
The patients were designed to receive alfentanil (group A, n = 70) or fentanyl (group F, n = 70) intravenous anesthesia. The patients were given midazolam 0.6 mg/kg and alfentanil 15 microgram/kg in group A or fentanyl 1.5 microgram/kg in group F. Propofol 0.7 mg/kg was given if patient was awaken during procedure. Hemodynamic changes, propofol used dosage and initial propofol injecting time, Ramsay Sedation Scales, cough reflex on opioid injection, recovery time, duration of apnea and postoperative nausea, vomiting at the recovery room were recorded.
Group A had rapid onset, deep sedation, less amount of propofol used, more frequent apnea than group F. There were no significant differences in postoperative nausea, vomiting and recovery time between the two groups.
The intravenous anesthesia with fentanyl or alfentanil are suitable for oocyte retreival but apnea happened more frequent in alfentanil group, so the use of alfentanil needs to monitor ventilation and hemodynamic changes carefully.
Key Words: alfentanil; fentanyl; oocyte retrieval
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