Korean J Anesthesiol Search


Korean Journal of Anesthesiology 2006;51(1):24-28.
DOI: https://doi.org/10.4097/kjae.2006.51.1.24   
Comparison of Total Intravenous Anesthesia and Sevoflurane-Alfentanil Anesthesia for Laparoscopic Cholecystectomy.
Eun Hye Koo, Hyun Jung Kim, Hee Zoo Kim, Hye Ran Oh, Il Ok Lee, Nan Sook Kim, Mi Kyung Lee
Department of Anesthesiology and Pain Medicine, Korea University School of Medicine, Seoul, Korea. mknim@hotmail.com
The aim of this prospective, double-blind randomized study was to compare the clinical properties of sevoflurane-alfentanil with propofol-remifentanil anesthesia in patients undergoing a laparoscopic cholecystectomy.
Forty patients (ASA physical status 1, 2) scheduled for elective surgery received total intravenous anesthesia (TIVA group) with remifentanil and propofol or sevoflurane-alfentanil. The TIVA group was induced with propofol 5 microgram/ml and remifentanil 4.5 ng/ml. The anesthesia was maintained with a continuous infusions of propofol 2.5 microgram/ml and remifentanil 3 ng/ml. The sevoflurane-alfentanil group was induced with alfentanil 15 microgram/kg and propofol 1.5 mg/kg IV. Maintenance was obtained with 2.0 vol% sevoflurane and a bolus of alfentanil 10microgram/kg IV where needed.
There were no significant differences in the systolic and diastolic blood pressure and heart rate between the two groups. There were no significant differences in the time to eye opening, the time to extubation, post-anesthetic recovery room stay time and the incidence of postoperative nausea and vomiting between the two groups.
Propofol-remifentanil (TIVA) and sevoflurane-alfentanil both provided satisfactory anesthesia for a laparoscopic cholecystectomy.
Key Words: alfentanil; propofol; remifentanil; sevoflurane; TIVA


Browse all articles >

Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: journal@anesthesia.or.kr                

Copyright © 2024 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next