Korean J Anesthesiol Search

CLOSE


Korean J Anesthesiol > Volume 46(3); 2004 > Article
Korean Journal of Anesthesiology 2004;46(3):317-322.
DOI: https://doi.org/10.4097/kjae.2004.46.3.317   
Thoracic Epidural Analgesia with 0.2% or 0.5% Bupivacaine during Upper Abdominal Operations.
Jae Young Kwon, Yeong Seo Park, Seong Wan Baik, Hae Kyu Kim, Sang Wook Shin, Chul Hong Kim
Department of Anesthesia and Pain Medicine, College of Medicine, Pusan National University, Busan, Korea.
Abstract
BACKGROUND
Thoracic epidural block has been widely used to control postoperative pain. The relative effects of the mass, volume, and concentration of local anesthetic solutions used are still subjects of debate, and the relationship between general anesthesia and thoracic epidural block is unclear.
METHODS
In study I, 20 conscious patients scheduled for elective upper abdominal surgery received 0.2% bupivacaine with morphine 3 mg (group CL: n = 10) or 0.5% bupivacaine with morphine 3 mg (group CH: n = 10) via an epidural catheter inserted at the T8-T9 epidural space. The width of sensory block, blood pressure and heart rate were assessed for 30 minutes and then general anesthesia was administered. In study II, under general anesthesia, 72 patients scheduled for elective upper abdominal surgery were injected with the same formula as used in study I (group UL: n = 36, group UH: n = 36). Blood pressure, heart rate, vol% of end-tidal inhalation agent were measured for an hour. Postoperatevely, the VAS scores of both study groups were assessed in the recovery room, after 24 hours and 48 hours.
RESULTS
In study I, the mean arterial pressures were significantly lower in the CH group than the CL group (P = 0.0419 and P = 0.0328 at 20 and 25 minutes after local anesthetic infusion), but heart rate and VAS score were not significantly different. In study II, no difference was observed between the groups in terms of blood pressure, heart rate, enflurane requirement, or VAS score. But hypotension requiring treatment was more frequent in the UH group than in the UL group (group UL: n = 3, group UH: n = 6).
CONCLUSIONS
Epidural administration of the same volume of 0.2% bupivacaine or 0.5% bupivacaine provided similar pain relief and hemodynamic change, but profound hypotension was more frequent in the 0.5% bupivacaine group during general anesthesia. This study shows no benefit of using 0.5% bupivacaine to improve postoperative analgesia in upper abdominal surgery.
Key Words: bupivacaine; thoracic epidural analgesia
TOOLS
Share :
Facebook Twitter Linked In Line it
METRICS Graph View
  • 0 Crossref
  •    
  • 1,182 View
  • 7 Download


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: journal@anesthesia.or.kr                

Copyright © 2023 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next