| Effect of Midazolam, Fentanyl and Propofol for Intravenous Anesthesia in Patients Undergoing the Cardioversion. |
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Mee Young Chung, Jun Seuk Chea, Chang Jae Kim, Hee Yeol Kim, Eun Ju Cho, Hee Sang Park, Byung Ho Lee |
1Department of Anesthesiology, College of Medicine, Catholic University, Seoul, Korea.
2Department of Cardiology Division, College of Medicine, Catholic University, Seoul, Korea.
3Department of Internal Medicine, College of Medicine, Catholic University, Seoul, Korea. |
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| Abstract |
BACKGROUND
Elective cardioversion is a short procedure performed under amnesia, sedation or anesthesia for the treatment of cardiac dysrhythmia. Midazolam, fentanyl and propofol on hemodynamic changes and side effects were studied.
METHODS
Thirty patients scheduled for an elective cardioversion in the coronary care unit received propofol 500microgram/kg I.V., followed by a continuous infusion with 25 75microgram/kg/min until they lost consciousness as determined by cessation of response to verbal command. All patients received midazolam 0.02 mg/kg and fentanyl 2microgram/kg I.V. 5 minutes before induction. In addition, the cardiologist administrated the electric shock. Blood pressures and heart rates were measured prior to induction, after the administration of midazolam and fentanyl, after cardioversion, 5 minutes after cardioversion and recovery.
The recovery time from terminating drug administration to awakening, and the total dose of propofol were recorded.
Patients were observed for side effects.
RESULTS
Systolic, mean, and diastolic blood pressures were significantly decreased 5 minutes after cardioversion and recovery. Heart rates were significantly decreased after cardioversion, 5 minutes after cardioversion and recovery.
Recovery times were 22.1 14.9 minutes and the total dose of propofol was 0.79 0.39 mg/kg. Incidence of apnea (> 30 s) was 30%.
CONCLUSIONS
We concluded that midazolam, fentanyl and propofol in patients undergoing an electric cardioversion decreased blood pressure and heart rate, but the cardiovascular status was maintained within clinically acceptable levels. |
| Key Words:
Anesthetics; fentanyl; midazolam; propofol; cardioversion; hemodynamics |
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