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Korean Journal of Anesthesiology 1969;2(1):75-81.
DOI: https://doi.org/10.4097/kjae.1969.2.1.75   
Clinical Investigation of Methoxyflurane: 100 Cases Report.
Huyug Taek Kim
Department of Anesthesiology, Medical School, Pusan National University, Korea.
Since Methoxyflurane, as a new potent, non-explosive, volatileanesthetic agent, was first studied by Van Poznak and Artusio in 1960, was administered to one hundred surgical patients. The following are the results of clinical observation. 1) Methoxyflurane is easily administered with a relatively simple vaporizer such as Heidbrink No.8 ether vaporizer in semi-closed system. 2) Anesthetic concentration is easily controlled with experience so that deep anesthesia can be avoided. 3) Excellent muscle relaxation is produced at intermediate levels of anesthesia without producing apnea. 4) Methoxyflurane is not irrttant to respiratory tract, not producing respiratory secretion. So that achoice of agent in respiratory disease. 5) Analgesia extends into the recovery phase, minimizing the need for narcotics in the immediate postopoerative period. 6) Induction and recovery from anesthesia is relatively prolonged. However, nausea, vomiting or delirium is less frequent than after ether anesthesia.


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