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Korean Journal of Anesthesiology 2009;57(4):499-502.
DOI: https://doi.org/10.4097/kjae.2009.57.4.499   
Allergic reactions after intravenous injection of methylprednisolone: A case report.
Jin Hun Chung, Ki Ryang Ahn, Hye Jung Chun, Chun Sook Kim, Kyu Sik Kang, Sie Hyeon Yoo, Ji Won Chung
Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Cheonan, Korea. ahnkiry@schca.ac.kr
Corticosteroid preparations have anti-inflammatory and immunosuppressive properties and are used widely for the treatment of allergic disorders and asthma. Steroids themselves, however, can induce hypersensitivity reactions. In this study, we report the case of a 66-year-old man with chronic obstructive pulmonary disease who exhibited an allergic reaction (rash, bronchospasm, bradycardia, severe hypotension and cardiac arrest) immediately after the intravenous injection of methylprednisolone sodium succinate. Despite cardiopulmonary resuscitation, sinus rhythm was not restored. The anesthesiologist should be aware that allergic reactions to corticosteroids can occur.
Key Words: Allergic reactions; Cardiopulmonary resuscitation; Corticosteroids


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