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Korean Journal of Anesthesiology 1991;24(3):635-641.
DOI: https://doi.org/10.4097/kjae.1991.24.3.635   
Cardiovascular Effects of Isoflurane in Korean Dogs .
Seok Hwa Yoon, Soo Chang Son, Jung Eun Lee, Se Jin Choi
Department of Anesthesiology, Chungnam National University, Taejeon, Korea.
Abstract
7 Korean dogs were anesthetized with oxygen and isoflurane in different concentrations (1 vo1.%, 2 vo1.%, 3 vo1.%). Cardiovascular effects of isoflurane in different concentrations were investigated. The results were as follow: 1) Heart rate was decreased significantly (p<0.05) following increase of isoflurane concentrations. 2) Mean arterial blood pressure was decreased significantly (p<0.05) following increase of isoflur- ane concentrations. 3) Cardiac index was decreased significantly (p<0.05) following increase of isoflurane concentra- tions. 4) Left ventricular stroke work index was decreased significantly (p<0.05) following increase of isoflurane concentrations. 5) Pumonary artery pressure and pumonary artery wedge pressure were decreased significantly (p<0.05) following increase of isoflurane, but there were no significant changes in central venous pressure, systemic vascular resistance and pulmonary vascular resistance.
Key Words: Cardiovascular effect; Isoflurane


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