| The Effects of Depolarizing and Nondepolarizing Muscle Relaxants on Postoperative Sore Throat , Hoarseness , and Myalgia. |
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Young Chul Woo, Hyung Mi Kim, Sang Ho Lim, Young Chul Park, Mi Kyung Lee, Nan Suk Kim, Young Seok Choi |
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Department of Anesthesiology, Korea University, College of Medicine, Seoul, Korea. |
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| Abstract |
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The relationship between different muscle relaxants(vecuronium, pancuronium, succinyl- choline) and postoperative sore throat, hoarseness, and myalgia was evaluated in 46 adult ASA class I women undergoing general anesthesia with endotracheal intubation. All patients were anesthetized with thiopental-N2O-O2 and enflurane. The patients were divided into 3 groups. Patients in group 1(n=15) were given vecuronium, group 2(n= 16) pancuronium, and group 3(n =15) succinylcholine. Patient interviews were conducted at 6~10 hours(h) and 24~30 h postoperatively.
Evaluation for severity of sore throat, hoarseness and myalgia was accomplished by scoring according to specific criteria. In groups 1, 2, and 3, 6~10 h postoperatively, the incidence of sore throat was 40%, 50%, and 33%; hoarseness was 40%, 31% and 27%; myalgia was 13%, 6% and 20% respectively. In groups 1, 2, and 3, 24-30 h postoperatively, the incidence of sore throat was 7%, 25%, and 53%; hoarseness was 13%, 31%, and 33%; myalgia was 13%, 19%, and 33% respectively. The use of succinyleholine(Sch) resulted in higher incidence of postoperative sore throat at 24-30 h compared with 6-10 h(p<0.05). These results suggest that administration of SCh may contribute to the occurence of postoperative sore throat. |
| Key Words:
Complications; Hoarseness; Myalgia; Sore throat; Neuromuscular relaxants; Vecuronium; Pancuronium; Succinylcholine |
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