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Korean Journal of Anesthesiology 1992;25(3):596-601.
DOI: https://doi.org/10.4097/kjae.1992.25.3.596   
The Effects of Depolarizing and Nondepolarizing Muscle Relaxants on Postoperative Sore Throat , Hoarseness , and Myalgia.
Young Chul Woo, Hyung Mi Kim, Sang Ho Lim, Young Chul Park, Mi Kyung Lee, Nan Suk Kim, Young Seok Choi
Department of Anesthesiology, Korea University, College of Medicine, Seoul, Korea.
The relationship between different muscle relaxants(vecuronium, pancuronium, succinyl- choline) and postoperative sore throat, hoarseness, and myalgia was evaluated in 46 adult ASA class I women undergoing general anesthesia with endotracheal intubation. All patients were anesthetized with thiopental-N2O-O2 and enflurane. The patients were divided into 3 groups. Patients in group 1(n=15) were given vecuronium, group 2(n= 16) pancuronium, and group 3(n =15) succinylcholine. Patient interviews were conducted at 6~10 hours(h) and 24~30 h postoperatively. Evaluation for severity of sore throat, hoarseness and myalgia was accomplished by scoring according to specific criteria. In groups 1, 2, and 3, 6~10 h postoperatively, the incidence of sore throat was 40%, 50%, and 33%; hoarseness was 40%, 31% and 27%; myalgia was 13%, 6% and 20% respectively. In groups 1, 2, and 3, 24-30 h postoperatively, the incidence of sore throat was 7%, 25%, and 53%; hoarseness was 13%, 31%, and 33%; myalgia was 13%, 19%, and 33% respectively. The use of succinyleholine(Sch) resulted in higher incidence of postoperative sore throat at 24-30 h compared with 6-10 h(p<0.05). These results suggest that administration of SCh may contribute to the occurence of postoperative sore throat.
Key Words: Complications; Hoarseness; Myalgia; Sore throat; Neuromuscular relaxants; Vecuronium; Pancuronium; Succinylcholine


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