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Korean Journal of Anesthesiology 1992;25(4):767-771.
DOI: https://doi.org/10.4097/kjae.1992.25.4.767   
The Prevention of Postoperative Nausea and Vomiting after Strabismus Surgery in Children.
Seung Kon Yang, Eun Chi Bang, Hae Keum Kil, Jong Rae Kim
Department of Anesthesiology, Yonsei University College of Medicine, Seoul, Korea.
Nausea and vomiting are common problems after strabismus surgery in pediatric patients. We compared the effects of droperidol and ephedrine with conventional regimen consisting of halothane-N2O to the effects of conventional regimen itself, 69 children. ASA physical status l, ages 1-12yrs, were studied. Each child was randomly assigned to receive droperidol 0.04mg/kg., ephedrine 0.5mg/kg or normal saline 2ml intramuscularly, 10 minutes before the end of surgery. The incidence of postanesthetic nausea and vomiting was 17% in the droperidol group(p<0.05)., 13% in the ephedrine group(p<0.05), which were significantly less than the control group(43%). But there was no significant difference between droperidol group and ephedrine group. We concluded that droperidol and ephedrine have significant postoperative antiemetic effect in patients undergoing strabismus surgery.
Key Words: Nausea and vomiting; Droperidol; Ephedrine; Antiemetic effect


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