A Study on Change in Serum K+, Na+ and Cl- Concentsations after Injection of Flaxedil-Pentothal Sodium-Succinyleholine.

Youn,  Byung Rae; Kim,  Ik Soo; Choi,  Se Jin

doi:1978.11.1.30

Clinical Research Article

Korean Journal of Anesthesiology 1978;11(1):30-33.
DOI: https://doi.org/10.4097/kjae.1978.11.1.30

A Study on Change in Serum K+, Na+ and Cl- Concentsations after Injection of Flaxedil-Pentothal Sodium-Succinyleholine.

Byung Rae Youn, Ik Soo Kim, Se Jin Choi

Department of Anesthesiology, Chungnam National University, College of Medicine, Daejon, Korea.

Abstract

Transient hyperkalemia is well known to occur in man following intravenous administration of succinylcholine chloride. To study on change of the serum level of K+, Na+ & Cl- after injection of succinylcholine in healthy adults, physical status 1 or 2 adopted by the American society of Anesthesiologists, we studied in two groups: pentothal sodium-succinylcholine injection group (group 1) as control, flaxedil-pentothal sodium-succinylcholine injetion group(group 2) as experimental. The following results were obtained: 1. Serum K+ was slightly increased in both groups, 2mEq/L at 3rd minute in control group, 2mEq/L at 1st minute in experimental group after succinylcholine injection, but no statistical significance was noticed in either group. 2. Serum Na+ was decreased 3 mEq/L immediately after pentothal sodium injection and then sliyhtly increased until 10th minute in control group. In experimental group lower level than control was observed until 15th minute, with the maximum decrease of 7mEq/L at 5th minute. But no statistical significance was noticed in either group. 3. Serum Cl was slightly decreased until 10th minute with the maximum decrease of 4mEq/L at 5th minute in control group. In experimental group, it was slightly increased until 5th minute. But no significance was noticed in either group.