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Korean J Anesthesiol > Volume 22(4); 1989 > Article
Korean Journal of Anesthesiology 1989;22(4):482-487.
DOI: https://doi.org/10.4097/kjae.1989.22.4.482   
The Cardiovascular Effects of Vecuronium during Anesthesia with Isoflurane.
Jung Seok Lee, Hae Kyu Kim, Inn Se Kim, Kyoo Sub Chung
Department of Anesthesiology, College of Medicine, Pusan National University, Pusan, Korea.
To investigate the cardiovascular effects of vecuronium during isoflurane anesthesia, I compared with effects of pancuronium. Eight mongrel dogs were anesthetized with intravenous thiopental sodium and maintained with oxygen (41/min)-isoflurane (1 MAC). Cardiovascular parameters were determined and recorded 1 minute before and 5, 10, 20, 30 minutes after administration of 3 times the ED, dose of pancuronium and vecuronium respectively. Only one neuromuscular relaxant was studied with each anesthetic administration. The results are as follows; 1) Pancuronium increased heart rate, mean arterial blood pressure, cardiac output. 2) Vecuronium caused no significant cardiovascular chanaes.
Key Words: Cardiovascular effects; Vecuronium; Pancuronium; Isoflurane
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