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Korean Journal of Anesthesiology 1982;15(1):74-80.
DOI: https://doi.org/10.4097/kjae.1982.15.1.74   
The Effect of Bupivacaine on the Methemoglobin Formation .
Yun Je Song, Chan Jin Park
Department of Anesthesiology, Chonnam University Medical School, Kwangju, Korea.
Abstract
The changes of methemoglobin concentration in the blood after the use of lidocatine or Marcaine were investigated in the human and the rabbits. In the human the drugs were give by the epidural route and intramuscularly in rabbits. Lidocaine did not increase the methemoglobin concentration in humans but marcaine increased the methemoglobin concentration in the blood.


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