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Korean Journal of Anesthesiology 2009;57(5):656-661.
DOI: https://doi.org/10.4097/kjae.2009.57.5.656   
Malignant hyperthermia during general anesthesia for a surgery of idiopathic scoliosis: A case report.
Han Young Kim, Young Ju Kim
Department of Anesthesiology and Pain Medicine, Eulji University Hospital, Daejeon, Korea. kyjdr@naver.com
Malignant hyperthermia is a potentially fatal hypermetabolic syndrome characterized by skeletal muscle rigidity and hyperpyrexia. We had an 11-year-old female presented for a surgery for idiopathic scoliosis of the thoracic vertebra. Generalized muscle rigidity and tachycardia were revealed 1 hour 35 minutes after isoflurane administration. Then the body temperature was risen to 43degrees C within 10 minutes and the arterial blood gas analysis showed a severe respiratory and metabolic acidosis. Under the suspicion of malignant hyperthermia, the patient was treated by discontinuing all anesthetic agents, hyperventilation with 100% oxygen, surface cooling with ice pack and the administration of dantrolene sodium. But, the patient died of renal failure and disseminated intravascular coagulation after 50 days postoperatively.
Key Words: Dantrolene sodium; Malignant hyperthermia; Scoliosis


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