Comparison of Dextrose Water and Hartmann's Solution in Each Low and High Doses for Adult Ambulatory Anesthesia: Effect on Recovery from Anesthesia.

Shin,  Young Hee; Ahn,  Hyun Joo; Choi,  Soo Joo; Lee,  Won Hung; Lee,  Byung Dal

doi:2007.52.1.55

Randomized Controlled Trial

Korean Journal of Anesthesiology 2007;52(1):55-61.
DOI: https://doi.org/10.4097/kjae.2007.52.1.55

Comparison of Dextrose Water and Hartmann's Solution in Each Low and High Doses for Adult Ambulatory Anesthesia: Effect on Recovery from Anesthesia.

Young Hee Shin, Hyun Joo Ahn, Soo Joo Choi, Won Hung Lee, Byung Dal Lee

¹Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. hjahn@smc.samsung.co.kr
²Department of Anesthesiology and Pain Medicine, Chungnam National University College of Medicine, Daejoen, Korea.

Abstract

BACKGROUND
Adequate fluid administration for ambulatory anesthesia has not been widely studied because most patients are healthy and operations are short durations and not invasive. However, long pre-operative nothing per os (NPO) time is known to affect post-operative complications like pain, headache, dizziness, drowsiness, fatigue, nausea, vomiting, thirsty, sore throat, or well-being sensation. And amount of administered fluid or inclusion of dextrose during the operation could exercise great influence on those symptoms. Therefore, we compared four fluid regimens; 5% dextrose water 2 ml/kg (D/W2), 20 ml/kg (D/W20) and Hartmann's solution 2 ml/kg (H/S2), 20 ml/kg (H/S20) regarding to post-operative complications of ambulatory anesthesia.
METHODS
One hundred and sixty ambulatory anesthesia patients of ASA 1 or 2 undergoing general anesthesia or monitored anesthesia care were randomly assigned into D/W2, D/W20, H/S2 or H/S20. Each group of patients received 5% dextrose water 2 ml/kg, 20 ml/kg, Hartmann's solution 2 ml/kg, or 20 ml/kg for 30 min, respectively. Complications like pain, headache, dizziness, drowsiness, fatigue, nausea, vomiting, thirsty, sore throat, or well-being sensation of patients were checked with systemized questionnaire check box graded 4 scales at recovery room, at evening and at 24 hours later.
RESULTS
H/S20 group was better in nausea, thirsty and well-being sensation. Sixteen percent of patients showed hypoglycemia before anesthesia. Dextrose water resulted transient hyperglycemia and osmotic diuresis.
CONCLUSIONS
Large amount of Hartmann's solution was generally better regarding post-operative complications. We should pay attention at peri-operative hypoglycemia for ambulatory anesthesia.