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Korean Journal of Anesthesiology 2007;53(3):356-360.
DOI: https://doi.org/10.4097/kjae.2007.53.3.356   
Comparison of Thiopental Sodium and Ketamine Induction on Emergence Agitation after Desflurane Anesthesia in Children undergoing a Tonsillectomy.
Han Seok Kim, Soo Kyung Lee, Hyo Seok Kang, Young Mi Kim, Hyun Choi, Hyun Soo Moon
Department of Anesthesiology and Pain Medicine, College of Medicine, Hallym University, Anyang, Korea. agnetask@yahoo.co.kr
Abstract
BACKGROUNDs
It is widely known that desflurane provides fast emergence but with a high incidence of emergence agitation. This study was designed to investigate the emergence agitation resulting from thiopental or ketamine induction with desflurane anesthesia for pediatric patients.
METHODS
Forty patients, aged 3-8 years, scheduled for a tonsillectomy or a tonsillectomy and adenoidectomy were randomly allocated into two groups. Anesthesia was induced using 5 mg/kg thiopental sodium (Group T patients) or 2 mg/kg ketamine (Group K patients), and was maintained using O2-N2O-desflurane. The recovery time and incidence of emergence agitation were assessed.
RESULTS
The incidence of emergence agitation was less in patients in the ketamine induction group. There were no differences in the recovery time and reported side effects.
CONCLUSIONS
We conclude that ketamine induction provides less emergence agitation when compared to thiopental induction for desflurane anesthesia for a pediatric tonsillectomy or a tonsillectomy and adenoidectomy without delayed recovery.
Key Words: desflurane; emergence agitation; ketamine; thiopental


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