| Epinephrine-induced Metabolic Acidosis during Orthognatic Surgery: A case report. |
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Sang Beom Nam, Yon Hee Shim, Young Chan Park, Yong Bum Kim, Jong Seok Lee |
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Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea. jonglee@yumc.yonsei.ac.kr |
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| Abstract |
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Epinephrine has a variety of clinical uses one is its use as a topical hemostatic agent on bleeding surfaces, such as in the mouth. We report a temporal association between the administration of topical epinephrine and the development of metabolic acidosis during general anesthesia. A 21 year-old patient, with facial asymmetry, had undergone orthognatic surgery. During the operation, serial blood gas analysis revealed the onset of a metabolic acidosis following the local infiltration (0.036 mg) and topical application of a high dose of epinephrine-Bosmin(R) (1:1,000 epinephrine).
The metabolic acidosis resolved within 5 hours. |
| Key Words:
epinephrine; metabolic acidosis |
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