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Korean J Anesthesiol > Volume 47(1); 2004 > Article
Korean Journal of Anesthesiology 2004;47(1):142-145.
DOI: https://doi.org/10.4097/kjae.2004.47.1.142   
Successful Treatment of Persistent Hiccups with Baclofen and Gabapentin: A case report.
Won Oak Kim, Kyung Bong Yoon, Hae Keum Kil, Duck Me Yoon, Kwan Sang Cho, Min Jeong Cho
1Departments of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.
2Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea. wokim@yumc.yonsei.ac.kr/drwokim@hanmail.net
Persistent hiccups are described as a recurring troublesome series of involuntary inspirations accompanied by glottic closure, lasting longer than a month. Recently, baclofen, the most effective treatment for intractable hiccups was found to be a useful drug for the management of chronic hiccups, and that substituting gabapentin for baclofen can be effective. Moreover, gabapentin was used successfully in combination with baclofen. We report here on three patients with persistent hiccups, where gabapentin was used successfully as an "add-on" with baclofen.
Key Words: baclofen; gabapentin; hiccups


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