Korean J Anesthesiol Search

CLOSE


Korean J Anesthesiol > Volume 37(1); 1999 > Article
Korean Journal of Anesthesiology 1999;37(1):19-24.
DOI: https://doi.org/10.4097/kjae.1999.37.1.19   
Postoperative Liver Function after Hepatic Resection with Hepatic Ischemic Insult under Enflurane Anesthesia.
Bong Il Kim, Chan Hong Park, Won Jae Kang
Department of Anesthesiology, School of Medicine, Catholic University of Taegu-Hyosung, Taegu, Korea.
Abstract
BACKGROUND
The most common cause of postoperative hepatic dysfunction is decreased hepatic blood flow due to decreased cardiac output and vasoactive substance during anesthesia. It might be suggested that hepatic blood flow occlusion affects postoperative dysfunction. This study was designed to investigate this possible effect on postoperative liver function.
METHODS
Forty-seven patients; hepatic resection with temporarily hepatic vascular occlusion (Pringle's maneuver) under enflurane anesthesia were involved. The duration of liver ischemia was 44.2 20.0 min. Blood transfusions (8.3 5.1 pints) were administered to nine patients intraoperatively. Aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and total bilirubin (TB) were measured at preoperation, postoperative 6 hours, 1, 3, 7 and 14 days. Alkaline phosphatase (AP) was measured also but not at postoperative 6 hrs.
RESULTS
The values of postoperative AST, ALT, LDH were increased sharply but returned at postoperative 7th day. AP did not change significantly. TB levels rose for 7 days postoperatively and then fell.
CONCLUSION
From these results, it is inferred that the effect of hepatic ischemic insult under enflurane anesthesia on postoperative liver function is not significant.
TOOLS
Share :
Facebook Twitter Linked In Line it
METRICS Graph View
  • 0 Crossref
  •    
  • 798 View
  • 2 Download


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: journal@anesthesia.or.kr                

Copyright © 2023 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next