Clinical Study of Propanidid as an Induction Agent ( Part III ) .

Park,  Dong Ho; Kim,  Wan Sik

doi:1970.3.1.83

Clinical Research Article

Korean Journal of Anesthesiology 1970;3(1):83-85.
DOI: https://doi.org/10.4097/kjae.1970.3.1.83

Clinical Study of Propanidid as an Induction Agent ( Part III ) .

Dong Ho Park, Wan Sik Kim

Department of Anesthesiology, Yonsei University School of Medicine, Seoul, Korea.

Abstract

Since 1966, Propanidid has been used not only for minor operative procedures but also as an induction agent. The present study was undertaken on 28 unselected cases from the daily operating schedule and blood gas analsis done before anesthesia and immediately after intubation with the aid of deporalizing muscle relaxants. Endotracheal intubation was performed intentionally preceding artificial oxygenation. The results of the blood gas study showed a mean PaO2 of 120. 2 mmHg, PaCO2-mean 41. 2 mmHg and pH-mean 7, 388 during respiratory depression following hyperpnea. As an induction agent, propanidid not only has no local complications but also gives smooth induction without excitatory phenomen and a rapid recovery. Further study on the interaction with nondeporalizing muscle relaxants is suggested.