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Korean Journal of Anesthesiology 1997;33(5):937-943.
DOI: https://doi.org/10.4097/kjae.1997.33.5.937   
Efficacy of Patient-Controlled Epidural Analgesia according to Changes of Continuous Background Infusion Volume.
Dong Hee Kim, Choong Hak Park, Sook Lee
Abstract
BACKGROUND
This study examined the efficacy of patient-controlled epidural analgesia (PCEA) for post-cesarean section pain control and compared the suitability of four different volumes of continuous background infusion (CBI).
METHODS
Sixty patients were received 0.125% bupivacaine with 5 g/ml fentanyl by PCEA (2 ml of demand dose and 10 minutes of lockout interval) and CBI. Experimental groups were divided four groups according to the volumes of CBI; 1 ml/hr, 2 ml.hr, 3 ml/hr and 4 ml/hr of CBI during 48 hours postoperatively.
RESULTS
Total amount of fentanyl and bupivacaine consumption was significantly higher in 1ml/hr of CBI group than 2 ml/hr of CBI group during first 24 hours, and in 4 ml/hr of CBI group than 1 ml/hr and 3 ml/hr of CBI group during second 24 hours. CBI/maximum hourly demand dose was 15~23%. There is no significant difference between the groups in pain score, side effects and patient's satisfaction.
CONCLUSIONS
This study suggests that two or three ml/hr of CBI can provide the most effective postoperative analgesia and the optimal ratio of CBI/maximum hourly demand dose is about 20%.
Key Words: Analgesia, patient-controlled, postoperative; Analgesics, fentanyl, bupivacaine


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