| Change of Whole Body Oxygen Consumption on Perfusion Flow Rate during Hypothermic Cardiopulmonary Bypass in Pediatric Patients. |
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Chong Sung Kim, Kwang Woo Kim |
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Department of Anesthesiology, Seoul National University College of Medicine, Seoul, Korea. |
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| Abstract |
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Whole body oxygen consumption(VO2) change related to selected arterial perfusion flow rate (Q) during profound hypothermic(20 degrees C) cardiopulmonary bypass were determined in 20 pediatric patients performing corrective surgery for Tetralogy of Fallot(TOF). VO2 fell progressively as Q decreased, from 23+/-17.8ml/min/m(2) at Q of 2.0 L/min/m to 23+/-20.0ml/min/m(2) at 1.5 L/min/m(2), 19+/-12.6ml/min/m at 1.0 L/min/m(2) at 1.0 L/min/m(2), and 17+/-11.5 ml/min/m(2) at 0.5 L/ min/m(2), Mixed venous oxygen partial pressure(PvO2 ) and saturation(SvO2) were decreased as perfusion flow rate decreased, but SvO2 was maintained above 65% even at the flow rate of 0.5 L/min/m(2). Oxygen extraction rate increased as perfusion rate decreased. There were no changes in mean arterial pressure related to change of perfusion flow rate. VO decrease at a certain perfusion flow rate between 1.0 and 0.5 L/min/m(2) but considred that SvO2 was above 65% and mean arterial pressure was maintained it is suggested that tissue oxygenation be adequate even at 0.5 L/min/m(2). |
| Key Words:
Cardiopulmonary bypass; Perfusion flow rate; Oxygen consumption |
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