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Korean Journal of Anesthesiology 1993;26(6):1120-1126.
DOI: https://doi.org/10.4097/kjae.1993.26.6.1120   
A Comparative Study of Inhalation Agent and Midazolam during Tracheal Intubation Using Nondepolaring N - M Blocker for The Anesthetic Induction.
Myoung Hoon Kong, Byoung Kuk Chae, Seong Ho Chang
Department of Anesthesiology, College of Medicine, Korea University, Seoul, Korea.
Because of various complicatins it's a trend to use non-depolarizing N-M blocker for the intubation, but oneset of action is delayed. So inhalation anesthetics are administered by mask until the onset time of action of N-M blocker which may cause pollution in operating room and it is possible for operating room personnel to bring up serious health problems. So, we used midazolam as adjuvant to induce general anesthesia and compared it with inhalation anesthetics for cardiovascular responses. Group E was given pentothal sodium 5mg/kg and inhaled 2% enflurane, group MP given midazolam O.lmg/kg and pentothal sodium 3mg/kg, and group M given only midazolam 0.3 mg/kg. As a N-M blocker O.lmg/kg of vecuronium bromide was given to all groups for endotracheal intubation. The results were as follows. 1. There was no significant difference in blood pressure and heart rate in each group. 2. Recovery time of consciousness at the end of anesthesia was longer in groups given midazolam. 3. The ratio of the patients who became asleep after the administration of O.lmg/kg of midazolam was 20% and 100% of patients became asleep with 0.3mg/kg of midazolam.
Key Words: Midazolam; Induction; Cardiovascular response
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