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Korean Journal of Anesthesiology 1990;23(3):373-380.
DOI: https://doi.org/10.4097/kjae.1990.23.3.373   
Clinical Experience of Pituitary Injectin of Phenol for Relief of Cancer Pain.
Chan Jin Park, Chang Young Jeong
1Department of Anesthesiology, Chonnam Medical School, Kwang-ju, Korea.
2Department of Pain Clinic, Chonnam Medical School, Kwang-ju, Korea.
Moriccas technique, neuroadenolysis of the pituitary gland through direct injection of alcohol, was performed 5 times on three cancer patients at chonnam university hospital. Two of the three patients had complete pain relief. During this procedure there was no any severe complications except diabetes insipidus, but it was treated uneventfully with indomethacin and fluid administration. Although several theories including destructiorr of the thalamic and hypothalamic nerve pathway, pituitary hormone and endorphin on the mechanism of pain relief by the neuroadenolysis have been reported, it is still not clearly determined. This technique is considered to be an exceedingly useful method for management of intractable pain in inoperable cancer patients.
Key Words: Pituitary neuroadenolysis; Cancer pain; Neurolytic agent


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