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Korean Journal of Anesthesiology 1990;23(4):563-567.
DOI: https://doi.org/10.4097/kjae.1990.23.4.563   
A Study of Changes in Plasma Norepinephrine and Epinephrine to Halothane.
Chong Sung Kim, In Cheol Choi, Kwang Woo Kim
Department of Anesthesiology, College of Mediciene, Seoul National University, Seoul, Korea.
The reaction to stress, while vital to the conscious animal, may be detrimental to the surgical patient. To assess the stress-associated action of halothane and its doses, we studied the responses in plasma norepinephrine, epinephrine, blood pressure and heart rate to changes of halothane concentration from 0 MAC to 1.5 MAC in 8 healthy adults. Systolic blood pressure, diastolic blood pressure and mean blood pressure were decreased as the concentration of the halothane increased from 0 MAC 0.5 MAC, 1.0 MAC and 1.5 MAC, respectively. But norepinephrine and epinephrine show no statistic ally significant response to changes in the concentration of halothane.
Key Words: Halothane; Anesthesia; Norepinephrine; Epinephrine


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