Korean J Anesthesiol Search

CLOSE


Korean Journal of Anesthesiology 1990;23(6):938-945.
DOI: https://doi.org/10.4097/kjae.1990.23.6.938   
Cardiovascular Changes by Endotrcheal Intubation According to Fentanyl-Diazepam Dosage.
Kwang Hee Choi, Jung Eun Lee, Sae Jin Choi
Department of Anesthesiology, College of Medicine, Chungnam National University, Korea.
Abstract
Induction of general anesthesia with tracheal intubation is a routine procedure, but it can result in significant tachycardia, hypertension, and arrhythmia. Many approaches have been tried to blunt these circulatory responses. We selected randomly 45 adult patients undergoing elective surgery at Chungnam National University Hospital. They were divided into three groups. Group I: Thiopental 5 mg/kg (n=15) Group II: Fentanyl 3ug/kg+Thiopental 4mg/kg (n=15) Goup lII: Diazepam 0.1 mg/kg+Fentanyl 10ug/kg+Thiopental 2 mg/kg (n=15) Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and heart rate (HR) were measured for 5 min after intubation. The results were as follow. Group I-intubation caused a significant rise in SBP, DBP, MAP, HR, (p<0.01) but each parameter except H.R, returned to normal within 5 min. Group II-intubation caused a significant rise in SBP, DBP, MAP, HR (p< 0.01), but each parameter returned to normal within 3 min. Group III-after intubation caused little cardiovascular change, but decreases significantly preintubation (p<0.01) It is concluded that diazepam and moderate dose of fentanyl can effectively prevent postintubation hypertension and tachycardia.
Key Words: Fentanyl; Diazepam; Endotracheal intubation


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
(서울특별시 마포구 마포대로 109 롯데캐슬 프레지던트 101동 3503호)
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: journal@anesthesia.or.kr                
Business Name: Korean Society of Anesthesiologists (대한마취통증의학회)
Business Registration: 106-82-07194
Representative: Jun Heum Yon (연준흠)

Copyright © 2024 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next