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Korean Journal of Anesthesiology 1992;25(3):509-514.
DOI: https://doi.org/10.4097/kjae.1992.25.3.509   
The Relationship between Blood Prssure , Heart Rate and Plasma Level of Catecholamine Concentration.
Chong Sung Kim, Chang Ho Kang, Kwang Woo Kim
Department of Anesthesiology, Seoul National University, College of Medicine, Seoul, Korea.
To evaluate the relationship between depth of anesthesia and plasma catecholamine concentration, the authors measured blood pressure(systolic, diastolic, mean), heart rate and plasma concentration of epinephrine and norepinephrine at varying condition of no anesthesia, under anesthesia and after stimulation. The subjects were 30 ASA class 1 surgical patients, aged from 20 to 40 years. Patients were given thiopental(4 mg/kg) and vecuronium(0.1 mg/kg) for induction and intubation. After 5 minutes controlled respiration with 100% oxygen, baseline measurements were taken. Measurements after 20 minutes maintenance with 1.7 vol % enflurane by end tidal concentration and measurement after skin incision were taken. Systolic pressure were 143.5+/-16.7, 107.6+/-15.0, 130.4+/-13,1lmmHg), and heart rate 115. 5+/-15.2, 85.1 +/-l5.3, 104.5+/-12.7(beat/min), plasma epinephrine concentration 93.6+/-48.4, 78.2+/-33.2, 77.0+/-23.5(ng/L), plasma norepinephrine concentration 451.6+/-154.7, 410+/-139.0, 376.7+/-104.3(ng/L), respectively. Systolic, diastolic and mean blood pressure showed significant change(p<0.05) but heart rate and plasma concentration of epinephrine and norepinephrine showed no significant changes.
Key Words: Enflurane; MAC; Catecholamine
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