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Korean Journal of Anesthesiology 1987;20(1):79-83.
DOI: https://doi.org/10.4097/kjae.1987.20.1.79   
The Responae of Myasthenia Gravis to Atracurium .
Won Oak Kim, Soon Ho Nam, Hee Soon Sa, Kyung Bong Yoon, Kwang Won Park
Department of Anesthesiology, Yonsei University College of Medicine, Seoul, Korea.
Generally, myasthenic patients are believed to have enhanced sensitivity with variety to the nondepolarizing neuromuscular blockade, even though some authors do not agree with that. Recent1y, the use of the new intermediate-acting nondepolarizing relaxant atracurium has been reported in patient with myasthenia gravis. The unique mode of elimination of atra-curium, which undergoes spontaneous degradation at physiologic body temperature and pH. may offer an advantage over the previously available Bong-acting muscle relaxants. We describe a case report of the anesthetic management of mysthenic patient using atracurium because of its relatilvely rapid rate of recovery. Reduced dosage of atracurium appeared to be a reasonable choice for myasthenic patients requring surgical relaxation when clinically indicated. However, continuous monitoring of neuromuscular function is of course mandatory for the proper and safe use of atracurium.


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