| Colloid Oncotic Pressure on the Effect of Survival Rate of ICU Patients. |
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In Young Chung, Shin Ok Koh, Wyun Kon Park, Hung Kun Oh |
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Department of Anesthesiology, Yonsei University College of Medicine, Seoul, Korea. |
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| Abstract |
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Colloid oncotic pressure (COP) plays a major role in regulating fluid exchange at the capillary membrane, and the magnitude of COP is determined by the concentration of large plasma proteins in the colloidal state. COP is also a determinant in the morbidity and mortality of critically ill patients. To assess the role of COP in these patients, clinical data including COP, age, sex, PaO2, PaCO2, AaDO2, mean arterial pressure, length of stay in ICU, duration of mechanical ventilation and whether surgical or non-surgical treatment, were collected and analyzed from those who were admitted to the Intensive Care Unit of Severance Hospital from March to July, 1986, The resvlts are as follows : 1) The mean values of COP, PaO2, Pacoa and AaDO2 are 15.07+/-2.89, 108.46+/-51.59 and 36.14+/-7.27 and 123.89+/-127.27 mmHg. 2) COP was the highest contributing factor to a survival prognosis followed by AaDO2, age, PaCO2 and surgery. 3) The level of COP was correlated with survival rates, and for a 50% survival rate, the level of COP was 13.5 torr. The above results suggest that COP is a contributing factor to the survival of patients admitted to the Intensive Care Unit. |
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