Korean Journal of Anesthesiology

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Original Article
Korean J Anesthesiol. 2006;50(5):511-514.
DOI: https://doi.org/10.4097/kjae.2006.50.5.511
Effect of Nitrous Oxide on Bispectral Index during Sevoflurane Anesthesia.
Kyoung Hun Kim, Yun Jeong Choi, Jae Hang Shim, Woo Jae Jeon, Sang Yoon Cho, Woo Jong Shin, Jong Hoon Yeom
Department of Anesthesiology and Pain Medicine, College of Medicine, Hanyang University, Seoul, Korea. yeomjh@hanyang.ac.kr
Abstract
BACKGROUND
Nitrous oxide is generally avoided in order to prevent either hypoxia or graft dislodgment during tympanoplasty. The aim of this study was to investigate the effect of nitrous oxide on the bispectral index during sevoflurane anesthesia at the anesthetic dose.
METHODS
The bispectral index was continually measured during nitrous oxide-oxygen-sevoflurane anesthesia, discontinuation of nitrous oxide and the reintroduction of nitrous oxide.
RESULTS
The bispectral index of nitrous oxide-oxygen-sevoflurane anesthesia increased after discontinuing the nitrous oxide and decreased after its reintroduction.
CONCLUSIONS
Nitrous oxide decreased the bispectral index of nitrous oxide-oxygen-sevoflurane anesthesia compared with oxygen-sevoflurane anesthesia at the anesthetic dose.

Keywords :bispectral index;nitrous oxide;sevoflurane

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