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Korean Journal of Anesthesiology 1979;12(4):456-459.
DOI: https://doi.org/10.4097/kjae.1979.12.4.456   
Effect of Mixed Intravenous Administration of Succinylcholine and Pancuronium on the Intraocular Pressure ( IOP ) .
Woong Mo Im, Chun Bong Lee
Department of Anesthesiology, Chonnam University Medical School, Kwangju, Korea.
Abstract
Succinylcholine has been reported to cause elevation of intraocular pressure(IOP.) IOP measurements, following single and mixed intravenous administration of succinylcholine and pancuronium, given immediately after thiopental, were made in 40 surgical patients, to assess the effect of pacuronium on the succinylcholine induced increase in IOP. The major findings of this study were as follows; 1) Tbiopental showed significant lowering effect on IOP. 2) A single intravenous injection of succinylcholine(1mg/kg) caused a slight rise of lOP. 3) A single intravenous injection of pancuronium(4mg) caused a slight decrease of IOP. 4) A mixed intravenous injection of succinylcholine and pancuronium increased the IOP more significantly than succinylcholine alone, This also means that pancuronium do not inhibit succinylcholine induced increase In IOP. 5) Tracheal intubation caused a rise of IOP significantly.


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