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Korean J Anesthesiol > Volume 55(1); 2008 > Article
Korean Journal of Anesthesiology 2008;55(1):52-56.
DOI: https://doi.org/10.4097/kjae.2008.55.1.52   
Effect of smoking on bronchial mucus transport velocity under total intravenous anesthesia.
Yong Han Kim, Young Jae Kim, Sang Eun Lee, Young Hwan Kim, Se Hun Lim, Jeong Han Lee, Kun Moo Lee, Soon Ho Cheong, Young Kyun Choi, Chee Mahn Shin
Department of Anesthesiology and Pain Medicine, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea. dr0216@hanmail.net
Abstract
BACKGROUND
The aim of this study was to measure the effect of smoking on bronchial mucus transport velocity with bronchoscope under total intravenous anesthesia.
METHODS
Twenty six ASA physical status I male patients (13 smokers and 13 nonsmokers) were enrolled into this study. They scheduled to undergo elective orthopedic surgery and were operated under total intravenous anesthesia using propofol and remifentanil. Single drop (approximately 0.02 cc) of methylene blue was applied to the posterior mucosal surface of right main bronchus 5 cm away from carina by the bronchoscope with epidural catheter 30 minutes after tracheal intubation. Two, four minutes after methylene blue application, the transport of methylene blue was observed. Six minutes after methylene blue application, the distance of methylene blue movement was measured.
RESULTS
Mean bronchial mucus transport distance and velocity of methylene blue in smoker group vs nonsmoker group was 9.1 +/- 5.5 mm and 1.5 +/- 1.0 mm/min vs 24.3 +/- 15.2 mm and 4.1 +/- 2.5 mm/min respectively. Mean bronchial mucus transport distance of methylene blue in the smoker group was shorter than that in the nonsmoker group (P value < 0.05). Mean bronchial mucus transport velocity of methylene blue in the smoker group was slower than that in the nonsmoker group (P < 0.05).
CONCLUSIONS
Smoking may delay transport of bronchial secretion in terms of bronchial mucus transport velocity under total intravenous anesthesia.
Key Words: bronchial mucus transport; smoking; total intravenous anesthesia


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