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Korean Journal of Anesthesiology 2009;56(1):79-82.
DOI: https://doi.org/10.4097/kjae.2009.56.1.79   
Anaphylaxis during patient transfer to the operating room following ranitidine administration: A case report.
Sung Wook Park, Hyung Seok Yoo, Joon Kyung Sung, Jae Woo Yi, Keon Sik Kim
Department of Anesthesiology and Pain Medicine, Medical College, Kyung Hee University, Seoul, Korea. keonsik@hanafos.com
Abstract
A 43-year-old male was admitted for reconstruction surgery to repair posterolateral rotatory instability of the knee. At the request of the surgeon, ranitidine was slowly administered intravenously immediately before the patient was transferred to the operating room to reduce the incidence of acid reflux. A few minutes later, during the transfer of the patient, anaphylaxis developed with hypotension, nausea, dyspnea, change in consciousness and urticaria. The patient had no previous history of any allergic tendency. After appropriate management, he recovered without complication. Following surgery, an allergic skin prick test was performed to determine if the patient was allergic to any of the drugs used during the surgery. According to the results, only ranitidine showed a positive reaction.
Key Words: Anaphylaxis; Ranitidine


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