Korean J Anesthesiol Search

CLOSE


Korean J Anesthesiol > Volume 56(2); 2009 > Article
Korean Journal of Anesthesiology 2009;56(2):140-145.
DOI: https://doi.org/10.4097/kjae.2009.56.2.140   
Effect of mixed administration of propofol and rocuronium on intubating conditions.
Hye Jin Jeung, Sang Hyun Kwak, Mai Ri, Cheol won Jeong, Seok Jai Kim, Hong beom Bae
Department of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Korea. shkwak@chonnam.ac.kr
Abstract
BACKGROUND
We investigated whether the intubating condition change acoording to the methods of administration of propofol and rocuronium.
METHODS
Ninety adult patients (ASA physical status I or II) undergoing elective surgery were randomly assigned to one of three groups; Group I (n = 30) received rocuronium (0.6 mg/kg) after administration of propofol (2 mg/kg), Group II (n = 30) received propofol and rocuronium simultaneously via different intravenous routes, and Group III (n = 30) received a mixture of propofol and rocuronium via same intravenous route. Intubation was attempted at 60 seconds after administration of rocuronium. Hemodynamic parameters (mean blood pressure, heart rate) were measured before and after propofol administration with 20 seconds interval. Intubating conditions (jaw relaxation, vocal cord movement, and response to tracheal intubation) were evaluated as excellent, good, fair and poor. Train of four counts were recorded at 60 seconds after administration of rocuronium.
RESULTS
Excellent intubating conditions were obtained in 13% in group I, 60% in group II, 77% in group III. Mean train of four counts were 3.7 in group I, 3.4 in group II, and 3.5 in group III. Mean blood pressures were decreased gradually after propofol administration in all groups. However, heart rates were not changed in all groups.
CONCLUSIONS
At induction of anesthesia, simultaneous or mixed administration of propofol and rocuronium provides excellent or good intubating conditions 60 seconds after rocuronium administration. It could be an effective alternative to succinylcholine for rapid sequence induction of anesthesia.
Key Words: Intubation condition; Mixture; Propofol; Rapid sequence induction; Rocuronium; Simultaneous injection
TOOLS
Share :
Facebook Twitter Linked In Line it
METRICS Graph View
  • 1 Crossref
  •   Scopus
  • 1,592 View
  • 42 Download


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: journal@anesthesia.or.kr                

Copyright © 2022 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next