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Korean Journal of Anesthesiology 2007;53(1):145-149.
DOI: https://doi.org/10.4097/kjae.2007.53.1.145   
Delayed Recovery of Neuromuscular Blockade by Rocuronium in a Patient with Charcot-Marie-Tooth Disease: Case reports.
Yong Kwan Cheong, Cheol Lee, Yong Son, Yoon Kang Song, Tai Yo Kim, Dea Jung Kim, Seri O
1Department of Anesthesiology and Pain Medicine, College of Medicine, Wonkwang University, Iksan, Korea. ykfolder@wonkwang.ac.kr
2Department of Oral and Maxillofacial Surgery, Daejeon Dental Hospital, College of Dentistry, Wonkwang University, Daejeon, Korea.
Charcot-Marie-Tooth disease, which is also known as hereditary motor and sensory neuropathy, is a heterogenous group of inherited diseases of the peripheral nerve. The spectrum of severity varies from asymptomatic individuals to those with severe limb abnormalities requiring corrective surgery. We report two brothers who had previously been diagnosed with Charcot-Marie- Tooth disease 3 years earlier and were scheduled to undergo a correction osteotomy of both feet under general anesthesia. General anesthesia was induced with propofol 2 mg/kg, rocuronium 0.8 mg/kg and was maintained with O2-N2O-Sevoflurane. The younger brother showed no delay in recovery of the neuromuscular blockade but the elder brother showed a delay.
Key Words: Charcot-Marie-Tooth disease; neuropathy; rocuronium


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