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Korean Journal of Anesthesiology 2007;53(6):746-752.
DOI: https://doi.org/10.4097/kjae.2007.53.6.746   
Postoperative Epidural Analgesia using 0.1% Levobupivacaine or 0.1% Ropivacaine Combined with Sufentanil in Gynecologic Surgery.
Chun Woo Yang, Jeong Min Park, Young Su Lim, Choon Kyu Cho, Kyong Sik Kim, Eung Kyun Kim, Sung Mee Jung
Department of Anesthesiology and Pain Medicine, College of Medicine, Konyang University, Daejeon, Korea. applejsm@hotmail.com
BACKGOUND: Ropivacaine and levobupivacaine are recently introduced amide local anesthetics that are structurally similar to bupivacaine. In this study, we compared the quality of postoperative analgesia and the side effects of 0.1% ropivacaine/sufentanil and 0.1% levobupivacaine/sufentanil.
Sixty patients scheduled for gynecologic surgery under general anesthesia were randomized to receive either 0.1% ropivacaine with sufentanil (ropivacaine group) or 0.1% levobupivacaine with sufentanil (levobupivacaine group) for postoperative epidural analgesia using a patient-controlled analgesia pump at a rate of 5 ml/h during the 48 hour period following surgery. Visual analogue scale (VAS) scores at rest and on coughing, sitting and movement, the degree of ambulation, additional analgesic requirements and side effects were assessed.
In the levobupivacaine group, VAS scores at rest and on coughing, sitting and movement were lower than in the ropivacaine group (P < 0.05). In the ropivacaine group more patients were able to walk unaided (P < 0.05). There were no differences in local anesthetic consumption, additional analgesic requirements and side effects between the groups.
Both 0.1% ropivacaine with sufentanil and 0.1% levobupivacaine with sufentanil provided effective postoperative epidural analgesia, but ropivacaine produced lesser motor block.
Key Words: epidural; gynecologic surgery; levobupivacaine; postoperative analgesia; ropivacaine; sufentanil


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