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Korean Journal of Anesthesiology 2006;50(3):341-345.
DOI: https://doi.org/10.4097/kjae.2006.50.3.341   
Anesthetic Management in a Patient with Charcot-Marie-Tooth Disease: A case report.
Eun Sung Kim, Hae Wone Chang, Won Jung Hwang, Yoon Ki Lee
Department of Anesthesiology and Pain Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. yklee@catholic.ac.kr
A 35-year old woman was scheduled to undergo a total hystectomy due to uterine myoma. She had been diagnosed with Charcot-Marie-Tooth disease 2 years ago. In addition, she had previously received a Cesarean section under epidural anesthesia 10 years ago and reported a prolonged motor blockade at that time. General anesthesia was induced with propofol 120 mg in a divided dose and the intubating condition was achieved with vecuronium 3 mg. Anesthesia was maintained with 1.5-2.5% enflurane with air and O2. During surgery, the body temperature and end tidal concentration of CO2 were maintained within the normal range. Despite the continuous monitoring of the train-of-four (TOF) response, no more muscle relaxants were required during surgery and the patient recovered without a delay in awakening. In the management of patients with Charcot-Marie-Tooth disease, it is desirable to evaluate the patient carefully, select the appropriate anesthetics and adjust the dosage of the drug according to the patients requirements.
Key Words: Charcot-Marie-Tooth disease; train-of-four (TOF) response; vecuronium


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