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Korean J Anesthesiol > Volume 50(3); 2006 > Article
Korean Journal of Anesthesiology 2006;50(3):361-364.
DOI: https://doi.org/10.4097/kjae.2006.50.3.361   
The Trial of Continuous Intravenous Infusion of Magnesium in Patients with Postherpetic Neuralgia Refractory in Conventional Treatment: A report of 2 cases.
Yong Kwan Cheong, Tai Yo Kim, Ju Hwan Lee
Department of Anesthesiology and Pain Medicine, School of Medicine, Wonkwang University, Iksan, Korea. ykfolder@naver.com
Abstract
Postherpetic neuralgia is one of the most troublesome diseases in pain clinics. The N-methyl-D-aspartate (NMDA) receptor antagonist, magnesium, reduces the level of neuropathic pain and hyperalgesia in patients with postherpetic neuralgia. Magnesium has been shown to exert a physiological block of the ion channel on the NMDA receptor, thereby preventing extracellular calcium ions from entering the cell and contributing to secondary neuronal changes. Accordingly, we attempted to administer a continuous intravenous infusion of magnesium, which resulted in a decrease in the VAS without side effects.
Key Words: magnesium; neuropathic pain; NMDA receptor antagonist; postherpetic neuralgia
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