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Korean J Anesthesiol > Volume 51(4); 2006 > Article
Korean Journal of Anesthesiology 2006;51(4):449-454.
DOI: https://doi.org/10.4097/kjae.2006.51.4.449   
Comparison of Anesthetic Techniques for Preventing Postoperative Nausea and Vomiting Undergoing Thyroidectomy.
Cheol Hun Choi, Seong Wook Jeong, Sung Tae Chung, Hong Beom Bae, Jeong Il Choi, Sung Su Chung, Kyung Yeon Yoo
Department of Anesthesiology and Pain Medicine, Medical School, Chonnam National University, Gwangju, Korea. anesman@jnu.ac.kr
Abstract
BACKGROUND
The aim of this study was to compare the anesthetic techniques for preventing postoperative nausea and vomiting (PONV) in the patients undergoing thyroidectomy.
METHODS
Sixty patients of ASA status I or II, undergoing thyroidectomy were studied. Patients were allocated randomly to one of three groups. Group 1 (n = 22): anesthesia was induced by propofol (2 mg/kg) and maintained with desflurane and 50% nitrous oxide in oxygen. Group 2 (n = 22): anesthesia was induced and maintained propofol and alfentanil using a computer controlled infusion system in 60% medical air in oxygen. Group 3 (n = 16): anesthesia was induced propofol using computer controlled infusion system in combination 50% nitrous oxide in oxygen. The incidence of PONV was assessed at 6 and 24 hours after the surgery and standardized by Rhodes index of nausea, vomiting and retching (RINVR) score.
RESULTS
In group 3, the incidence of PONV within the first 6 hours after surgery, was significantly lower as P < 0.05. But, there was no statistical differences among the three groups in the 6 to 24 hours' RINVR score after surgery.
CONCLUSIONS
The use of propofol for induction and maintenance with combination 50% N2O is the most effective technique at preventing PONV among the three groups within the first 6 hours after thyroidectomy. This study found no statistically significant difference between the RINVR score, using desflurane-N2O and propofol-alfentanil.
Key Words: anesthetics; postoperative nausea and vomiting; thyroidectomy
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