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Korean Journal of Anesthesiology 2003;45(2):205-209.
DOI: https://doi.org/10.4097/kjae.2003.45.2.205   
The Effect of Epidural Butorphanol for Analgesia after Cesarean Section.
Jong Nam Ji, Yoon Hee Kim, Yong Sup Shin
Department of Anesthesiology and Pain Medicine, Chungnam National University College of Medicine, Daejeon, Korea. ysshin@cnu.ac.kr
This study aimed to compare analgesic efficacy and the side effects of postoperative continuous epidural infusion (2 ml/hr) of morphine (40 microgram/ml) or butorphanol (50 microgram/ml) administered with 0.15% ropivacaine 100 ml.
Forty consenting, healthy, term parturients who had undergone Ceasarean section under epidural lidocaine and ropivacaine anesthesia received a morphine 1 mg bolus and 0.15% ropivacaine 100 ml/morphine 4 mg (Group M, n = 20) or a butorphanol 2 mg bolus and 0.15% ropivacaine 100 ml/butorphanol 5 mg (Group B, n = 20) using an epidural 2 day infuser (2 ml/hr) 30 minutes after surgical incision.
No significant difference were observed by the visual analog scale (VAS) for pain during rest, but Group B requested significantly greater amounts of supplementary diclofenac sodium during the first 24 hours. Side effects were higher in pruritus in Group M and in somnolence in Group B, but no significant differences in severe side effects were evident between the two groups.
Using 0.15% ropivacaine 100 ml with morphine (40 microgram/ml) via an epidural 2 day infuser (2 ml/hr) provided better pain relief than butorphanol (50 microgram/ml) group, but significant side effects, such as pruritus, were observed.
Key Words: analgegics; butorphanol; morphine; postoperative pain


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