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Korean J Anesthesiol > Volume 45(5); 2003 > Article
Korean Journal of Anesthesiology 2003;45(5):601-605.
DOI: https://doi.org/10.4097/kjae.2003.45.5.601   
Effect of Acute Normovolemic Hemodilution on Homologous Blood Saving during Off-Pump CABG.
So Ron Choi, Ji Yoon Kim, Young Jhoon Chin
Department of Anesthesiology, College of Medicine, Donga University, Busan, Korea. yjjin@daunet.donga.ac.kr
Abstract
BACKGROUND
Acute normovolemic hemodilution (ANH) is accepted to be the easiest and most economical method of autotransfusion. This study was performed to investigate the clinical usefulness of ANH in patients undergoing off-pump CABG.
METHODS
Thirty patients were randomly divided into two groups. In the ANH group, 753.3 +/- 51.6 ml of fresh autologous whole blood were sequestrated from a pulmonary artery catheter following induction of anesthesia with simultaneous infusion of colloids and crystalloid solution from a separate line. Perioperative changes of hemoglobin, hematocrit level, platelet counts, prothrombin time, cardiac output, transfusion requirement and the amount of postoperative drainage were compared between the two groups.
RESULTS
Perioperative changes of platelet counts and PT showed no significant differences between the two groups. Less allogenic blood was used in the ANH group (0.27 +/- 0.46 unit) than in the control group (1.27 +/- 0.80 unit) in the operation room.
CONCLUSIONS
ANH can decrease the transfusion requirement in off-pump CABG.
Key Words: acute normovolemic hemodilution; allogenic transfusion; autotransfusion; coronary artery bypass graft


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