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Korean Journal of Anesthesiology 2005;48(1):10-14.
DOI: https://doi.org/10.4097/kjae.2005.48.1.10   
A Comparison of the Effects of Propofol and Sevoflurane Anesthesias on Intraocular Pressure during Laparoscopic Hysterectomy.
Youn Suk Son, Sae Cheol Oh, Kyu Don Chung, Kook Hyun Kim, Keon Jung Yoon
Department of Anesthesiology and Pain Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. ane85@hanmail.net
Abstract
BACKGROUND
Laparoscopic surgery in the Trendelenburg position affects the cardiopulmonary system and may also influence intraocular pressure (IOP). The purpose of this study was to compare the effects of propofol and sevoflurane anesthesias on IOP change during laparoscopic hysterectomy.
METHODS
Thirty-one women were randomly allocated to either a propofol (P-group, n = 15) intravenous anesthesia group or a sevoflurane (S-group, n = 16) inhaled anesthesia group with fentanyl-N2O/O2-vecuronium. Heart rate, mean arterial pressure, plateau airway pressure, ETCO2, and IOP were measured before induction (T1), 10 min after induction (T2), 10 min after pneumoperitoneum in the Trendelenburg position (T3), and 5 min after pneumoperitoneum deflation in the horizontal position (T4).
RESULTS
IOP was significantly decreased in both groups after induction. IOP was increased in both groups after pneumoperitoneum in the Trendelenburg position, but IOP in the sevoflurane group was significantly higher than that in the propofol group.
CONCLUSIONS
Propofol intravenenous anesthesia may be a better choice for IOP control during laparoscopic surgery.
Key Words: intraocular pressure; laparoscopic surgery; propofol; sevoflurane; trendelenburg position


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