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Korean Journal of Anesthesiology 2000;38(4):606-612.
DOI: https://doi.org/10.4097/kjae.2000.38.4.606   
Alterations in Arterial Blood Gas and Electrolytes Following Crystalloid Infusion during Orthopedic Surgery.
Chang Kil Park
Department of Anesthesiology, Eulji University School of Medicine, Taejon, Korea.
The purpose of this study is to evaluate the effects of crystalloid solutions on the arterial blood gas and electrolytes in spinal (n = 58) and hip joint surgery (n = 2).
Sixty patients were randomly divided into three groups according to the kind of crystalloid solutions. Group 1 patients (n = 20) received Hartmann's solution (HS), group 2 patients (n = 20) received HS plus normal saline (NS) in a 1 : 1 volume ratio, and group 3 patients (n = 20) received NS. Arterial blood gas and electrolytes were measured after induction and at the end of the operation.
The replacement volumes of the crystalloid solutions in groups 1, 2 and 3 were 2545 +/- 931, 3050 +/- 1013 and 3240 +/- 1056 ml, respectively. The degree of the change in pH from after induction until the end of the operation was the greatest in group 3 (0.125) than in group 1 (0.04) and group 2 (0.079) (p < 0.05). The degree of the changes in the serum chloride value in groups 2 (9.1 mEq/L) and 3 (12.1 mEq/L) was greater than that in group 1 (4.2 mEq/L), respectively (p < 0.05). In the relationships among the parameters in group 3, the pH values tended to decrease with increasing volume replacements of NS (P = 0.005); and the chloride values tended to increase with increasing volume replacements of NS (P = 0.005).
The results suggest that HS is the superior crystalloid solution because there were less changes in acid-base balance and chloride value than when NS was infused alone. HS did not alleviate the changes of acid-base balance and chloride value caused by NS when both of them were infused at the same time.


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