Korean J Anesthesiol Search

CLOSE


Korean J Anesthesiol > Volume 39(1); 2000 > Article
Korean Journal of Anesthesiology 2000;39(1):14-18.
DOI: https://doi.org/10.4097/kjae.2000.39.1.14   
Effect of Lidocaine and Metoclopramide on Vascular Pain Associated with Intravenous Propofol Injection.
Wha Ja Kang, Su Sang Jung, Keon Sik Kim
Department of of Anesthesiology, College of Medicine, Kyung-Hee University, Seoul, Korea.
Abstract
BACKGROUND
Propofol has a high incidence of pain with intravenous injection, and different methods have been used to minimize the incidence and severity of this pain. In this study, we have compared the effect of lidocaine pretreatment with that of metoclopramide pretreatment on propofol injection pain.
METHODS
Ninety healthy female patients scheduled for general anesthesia were randomly divided into three groups; saline group (n = 30), lidocaine group (n = 30) and metoclopramide groups (n = 30). Each patient received 2 ml of pretreatment solution (normal saline, 1% lidocaine, 0.5% metoclopramide) via 18 G angiocatheter inserted in the antecabital fossa after applying an arm tourniquet inflated to 50 mmHg. The tourniquet was released 1 minute later, followed by intravenous injection of 2.5 mg/kg of propofol. The assesement of pain was made at the induction of anesthesia and in the recovery room and the severity of pain was classified as none, mild, moderate, severe by one observer.
RESULTS
The severity and incidence of pain diminished significantly in the lidocaine group and the metoclopramide group compared with the saline group at the induction of anesthesia (P < 0.05) and there was no significant difference between the lidocaine group and metoclopramide group. We had similar results in the recovery room and one patient from the saline group and the metoclopramide group had no recall regarding injection pain.
CONCLUSIONS
Intravenous metoclopramide pretreatment is as effective as intravenous lidocaine pretreatment in alleviating the propofol injection pain.
Key Words: Anesthetics; intravenous: propofol; pain; Anesthetics, local: lidocaine; Pharmacology, antiemetics: metoclopramide
TOOLS
Share :
Facebook Twitter Linked In Line it
METRICS Graph View
  • 0 Crossref
  •    
  • 953 View
  • 16 Download


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: journal@anesthesia.or.kr                

Copyright © 2023 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next